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Grand Central is the business area surrounding landmark Grand Central Terminal at 42nd and Park. The district runs roughly from 34th to 50th street, and from 3rd to 5th Avenue.

Midtown Manhattan is the busiest single commercial district in the United States, and the Grand Central Area represents a very crucial part of it. Home to such famous landmarks as the MetLife Building and the CitiCorp Center, Grand Central District is known for being all business. Madison Avenue in this area is famous for its advertising firms, representing the highest concentration of advertising in the world. Many banks and other financial firms are located here, as well as the Grand Central transportation hub. The district's most famous building, the Chrysler Building, is still a landmark skyscraper at over 70 years old, and has prestigious Class A Office Space.

Grand Central is an ideal place for business centered around Grand Central Terminal, especially commuters from Westchester, Connecticut, and other points served by Metro North. Holding some of the best Class A Space in Manhattan, Grand Central is ideal for firms with the money to spend looking to be in a prestigious location in east Midtown. Rents are still lower than the nearby Plaza District, however. With the area's bars and restaurants, there is always activity.