Rent Office 380 Second Avenue

Rent Sublease Office - 380 Second Ave

$ / SF SF Monthly Rent
$ / SF SF Monthly Rent
$ / SF SF Monthly Rent
Rent Coworking Office
Type of Space Class A Class B Class C
Windowed office/person $ 2,000/mo $ 1,250/mo $ 750/mo
Interior office/person $ 1,250/mo $ 750/mo $ 500/mo

Nearby office Spaces for Rent

Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Madison Ave & East 25th Street $ 86 7,400 $ 52,725
Madison Ave & East 25th Street $ 90 5,000 $ 37,500
Madison Ave & East 26th Street $ 79 2,600 $ 17,187
Madison Ave & Between East 23rd Street $ 124 4,700 $ 48,370
Fifth Ave & Between East 22nd Street $ 83 6,400 $ 44,333
Address $ / SF SF Monthly Rent
Madison Ave & East 25th Street $ 86 83,100 $ 592,087
Madison Ave & East 25th Street $ 80 13,100 $ 87,333
Address $ / SF SF Monthly Rent
Union Sq W & Broadway $ 51 1,000 $ 4,249
Park Ave S & East 18th Street $ 49 2,000 $ 8,187
Union Sq W & East 14th Street $ 45 1,600 $ 6,000
Park Ave S & East 17th Street $ 62 1,700 $ 8,712
Address $ / SF SF Monthly Rent
Union Sq W & Broadway $ 37 2,800 $ 8,575
Park Ave S & East 18th Street $ 49 5,300 $ 21,696
Madison Ave & East 29th Avenue $ 36 8,500 $ 25,234
Address $ / SF SF Monthly Rent
Union Sq W & Broadway $ 37 11,300 $ 34,606
Fifth Ave & East 21st Street $ 47 11,200 $ 44,100
Park Ave S & East 18th Street $ 49 10,700 $ 43,803
Broadway & East 17th Street $ 43 12,800 $ 45,600
E 23rd St & Park Avenue $ 33 18,400 $ 51,175
Address $ / SF SF Monthly Rent
E 23rd St & Park Avenue $ 39 2,200 $ 7,150
E 28th St & Park Avenue South $ 26 1,300 $ 2,762
E 23rd St & Broadway $ 27 1,400 $ 3,185
Address $ / SF SF Monthly Rent
E 16th St & Fifth Avenue $ 31 8,000 $ 20,600
E 23rd St & Park Avenue $ 39 3,000 $ 9,750
E 19th St & Broadway Negotiable 5,500 Negotiable
E 23rd St & Park Avenue South $ 27 3,200 $ 7,280
Address $ / SF SF Monthly Rent
Madison Ave & East 30th Street $ 29 11,300 $ 27,119
Broadway & East 18th Street $ 68 11,500 $ 65,549
Broadway & Between East 12th Street $ 29 13,600 $ 33,320

Rent Nearby Coworking Office

Type of Space Class A Class B Class C
Windowed office/person $ 2,000/mo $ 1,250/mo $ 1,000/mo
Interior office/person $ 1,250/mo $ 750/mo $ 500/mo

Retail Spaces for Rent

Nearby retail Spaces for Rent

Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Fifth Ave & Between East 22nd Street Negotiable 1,400 Negotiable
Address $ / SF SF Monthly Rent
Fifth Ave & Between East 22nd Street Negotiable 9,800 Negotiable
Madison Ave & Between East 23rd Street Negotiable 16,500 Negotiable
Madison Ave & East 26th Street Negotiable 4,600 Negotiable
Madison Ave & East 28th Street Negotiable 6,200 Negotiable
First Ave & East 22nd Street $ 162 2,200 $ 29,749
Address $ / SF SF Monthly Rent
Park Ave S & East 24th Street Negotiable 900 Negotiable
E 17th St & Park Avenue South Negotiable 500 Negotiable
Second Ave & East 23rd Street Negotiable 900 Negotiable
Address $ / SF SF Monthly Rent
Park Ave S & East 24th Street Negotiable 1,700 Negotiable
Park Ave S & East 17th Street Negotiable 1,200 Negotiable
Gramercy Park S & East 19th Street Negotiable 1,800 Negotiable
Second Ave & East 23rd Street Negotiable 1,800 Negotiable
Park Ave S & East 29th Street Negotiable 1,900 Negotiable
Bleecker St & Between Macdougal street Negotiable 1,100 Negotiable
E 23rd St & Third Avenue Negotiable 1,600 Negotiable
Address $ / SF SF Monthly Rent
Fifth Ave & East 17th Street Negotiable 4,200 Negotiable
Park Ave S & East 17th Street Negotiable 7,800 Negotiable
Union Sq E & East 15th Street Negotiable 10,900 Negotiable
E 17th St & Park Avenue South Negotiable 2,200 Negotiable
Irving Pl & Between East 15th Street Negotiable 6,400 Negotiable
Union Sq W & East 17th Street Negotiable 4,800 Negotiable
Union Sq W & Broadway Negotiable 3,000 Negotiable
Fifth Ave & East 17th Street Negotiable 6,200 Negotiable
Park Ave S & East 20th Street Negotiable 3,700 Negotiable
E 17th St & Fifth Avenue $ 104 2,400 $ 20,800
W 145th St & Between Broadway $ 77 4,500 $ 29,043
Park Ave S & East 29th Street Negotiable 9,700 Negotiable
Union Sq W & East 14th Street Negotiable 7,200 Negotiable
Fifth Ave & East 21st Street $ 61 5,500 $ 28,141
Fifth Ave & East 29th Street Negotiable 6,000 Negotiable
Fifth Ave & Between East 17th Street Negotiable 2,500 Negotiable
Fifth Ave & East 19th Street Negotiable 2,200 Negotiable
Address $ / SF SF Monthly Rent
Union Sq W & East 16th Street Negotiable 600 Negotiable
E 28th St & Park Avenue South Negotiable 800 Negotiable
Broadway & East 13th Street Negotiable 600 Negotiable
Address $ / SF SF Monthly Rent
Fifth Ave & Between East 28th Street Negotiable 1,900 Negotiable
Park Ave S & East 25th Street Negotiable 1,100 Negotiable
Fifth Ave & East 17th Street Negotiable 1,900 Negotiable
E 23rd St & Broadway $ 180 1,500 $ 22,500
Address $ / SF SF Monthly Rent
E 20th St & Third Avenue $ 168 3,200 $ 44,778
Union Sq W & East 16th Street Negotiable 8,500 Negotiable
Fifth Ave & Between East 28th Street Negotiable 4,300 Negotiable
Broadway & East 13th Street Negotiable 4,300 Negotiable
E 23rd St & Park Avenue $ 115 2,500 $ 23,958
E 19th St & Broadway $ 48 5,500 $ 22,000
E 18th St & Broadway Negotiable 8,900 Negotiable
Broadway & Between East 12th Street Negotiable 9,000 Negotiable

Rent Medical Space

Nearby medical Spaces for Rent

Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
3rd Ave & Union Street $ 58 1,100 $ 5,362
Park Ave S & East 26th Street Negotiable 2,600 Negotiable
Union Sq E & East 15th Street Negotiable 1,200 Negotiable
Address $ / SF SF Monthly Rent
Madison Ave & East 29th Street Negotiable 3,300 Negotiable
Union Sq E & East 15th Street Negotiable 3,100 Negotiable
Union Sq W & East 17th Street Negotiable 4,200 Negotiable
Address $ / SF SF Monthly Rent
E 23rd St & Park Avenue Negotiable 6,100 Negotiable
Madison Ave & East 29th Street Negotiable 13,400 Negotiable
Address $ / SF SF Monthly Rent
E 20th St & Third Avenue $ 59 1,000 $ 4,916
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
380 Second Avenue nyc
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Lease 380 Second Avenue

Rent 380 Second Avenue Property Overview

Bulding Address: 380 Second Ave
Building Alternate address: 380 2nd Ave
Zip Code:10010
Neighborhood:Gramercy Park
Borough:Manhattan
Stories:10
Year Built:1909
Building Class:B
Block & lot:00927-0055


The Gramercy Medical Arts Building, located at 380 Second Avenue in Manhattan, NYC, has a rich history dating back to the early 20th century. Constructed in 1909, it is situated in the Gramercy Park neighborhood and stands as a significant example of the area's development and transformation over time.

Originally built as a general office building, it has undergone transformations to become a hub for medical and educational institutions. The building was recently rebranded as the Gramercy Medical Arts Building due to its prominent tenants in the healthcare, arts, and education sectors.

It features a total of 182,258 square feet, spread across 10 stories. The building includes notable facilities such as bio-tech/lab spaces and offers amenities like 24-hour access, security systems, and Wi-Fi.

Current tenants include renowned institutions like NYU Langone Health, the Hospital for Joint Diseases, New York University, and the School of Visual Arts, reflecting its strategic importance in "Medical/Education Alley."

380 Second Avenue, Manhattan, NYC is also known as the Gramercy Medical Arts Building. Located in the heart of "Medical/Education Alley," it serves as a hub for renowned medical and educational institutions. The building stands 10 stories tall, offering 198,000 square feet of Class B office space with 20,000 rentable square foot floor plates. It features amenities like 24-hour access, biotech/lab space, concierge service, on-site management, security, high ceilings, and tenant-controlled HVAC. The property includes two handicapped-accessible lobbies and a private loading dock on 22nd Street, making it ideal for healthcare-related businesses and medical practitioners. Notable tenants include NYU Langone Health, NYU's Department of Physical Therapy, Mt. Sinai's New York Eye & Ear Infirmary, and the School of Visual Arts.


Building Amenities at 380 Second Avenue, Manhattan, NYC

  • 24-hour access
  • Biotech/lab space
  • Concierge service
  • On-site property management and security
  • High ceilings
  • Tenant-controlled HVAC
  • 300-pound floor loads
  • Two handicapped-accessible lobbies
  • Private loading dock on 22nd Street
  • Medical office features including hardwood floors, good natural light, and north and west views along 2nd Avenue
  • Existing buildout with reception area, consultation room, exam rooms with sinks and built-in cabinetry, lab room, and private restroom
  • Long-term stable ownership with ongoing renovation and expansion of second lobby at 310 East 22nd Street

Office Tenants at 380 Second Avenue, Manhattan, NYC

380 Second Avenue is a prominent 10-story Class B office and medical building located in Manhattan’s Gramercy Park neighborhood. Known as the Gramercy Medical Arts Building, it hosts a prestigious roster of tenants primarily from healthcare, medical, and educational sectors.

  • Gramercy Surgery Center
  • NYU Langone Health
  • NYU’s Department of Physical Therapy and College of Dentistry
  • NYU Langone Hospital's Diagnostic Imaging Center
  • Hospital for Joint Diseases (NYU Langone)
  • Mt. Sinai’s New York Eye & Ear Infirmary
  • School of Visual Arts
  • MedRite
  • East Side Endoscopy
  • Gramercy Surgical Center

The building features amenities including tenant-controlled HVAC, 24-hour access, concierge service, on-site property management and security, high ceilings, biotech/lab space, and a private loading dock. The floors have a 300-pound load capacity and benefit from abundant natural light, with the upper floors offering views of the NYC skyline.


Internet Providers at 380 Second Ave, Manhattan, NYC:

Although specific providers at this location are not listed, typical internet providers in Manhattan include:

  • Verizon Fios: Known for high speeds and reliable fiber-optic service.
  • Astound Broadband Powered by RCN: Offers cable and fiber services with competitive pricing.
  • Spectrum: Provides widespread cable internet coverage across Manhattan.
  • Other Options: T-Mobile Home Internet and fixed wireless providers like STARRY may also be available.

For precise availability, contacting each provider directly is recommended.

380 Second Avenue is located in the heart of Manhattan's Gramercy Park neighborhood. It is easily accessible by public transportation.

Nearest Subway Stations: - 23rd Street (R, W trains) - 14th Street – Union Square (4, 5, 6, L, N, Q, W trains)

Bus Lines: - BM3, M101, M15-SBS, M23-SBS, M34A-SBS

Cross Streets: - First Avenue and Second Avenue

Public Transportation Directions: - To get there by subway, take the R or W train to 23rd Street and exit towards 2nd Avenue. - For bus, take any of the bus lines mentioned above and get off at the nearest stop to 2nd Avenue and 23rd Street.

Rent Office - 380 Second Avenue Average

Year $ / SF
2018 67.0
Year$ / SF

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