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Rent/Lease Office 450 W 126th St

Lease Office 450 W 126th St

$ / SF SF Monthly Rent
Negotiable

Rent Sublease Office at 450 W 126th St

Nearby Sublease office Spaces for Rent

Address $ / SF SF Monthly Rent
W 57th St & Avenue of the Americas $ 112
25,000
$ 232,291
Avenue of the Americas & West 55th Street West 56th Street $ 62
7,300
$ 38,020
Madison Ave & East 54th Street $ 80
31,000
$ 207,958
Avenue Of The Americas & West 47th Street $ 56
10,000
$ 46,666
Park Ave & East 57th Street $ 160
10,800
$ 144,000
Madison Ave & East 59th Street $ 100
8,300
$ 68,820
Fifth Ave & West 52nd Street $ 130
10,300
$ 111,583
Address $ / SF SF Monthly Rent
Park Ave & East 54th Street $ 86
5,600
$ 40,133
Fifth Ave & East 56th Street $ 86
6,600
$ 47,300
Lexington Ave & East 50th Street $ 54
4,000
$ 18,000
Avenue of the Americas & West 55th Street West 56th Street $ 62
6,200
$ 32,033
Madison Ave & East 49th Street $ 69
5,500
$ 31,625
Address $ / SF SF Monthly Rent
Madison Ave & East 49th Street $ 77
2,200
$ 14,116
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
E 60th St & Madison Avenue $ 66
4,200
$ 23,100
W 57th St & Avenue of America $ 532
5,100
$ 226,100
Address $ / SF SF Monthly Rent
W 57th St & Avenue of America $ 532
2,300
$ 101,870
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person
Interior office/person
Team Rooms
Suites

Nearby office Spaces for Rent

Address $ / SF SF Monthly Rent
W 57th St & Avenue of the Americas $ 105
15,800
$ 138,250
Fifth Ave & East 55th Street $ 158
19,300
$ 254,116
Park Ave & East 58th Street $ 125
11,300
$ 117,708
Address $ / SF SF Monthly Rent
Third Ave & East 49th Street $ 50
4,300
$ 17,916
Park Ave & East 54th Street $ 80
3,500
$ 23,479
Park Ave & East 58th Street $ 125
4,000
$ 41,666
Third Ave & East 49th Street $ 73
3,800
$ 23,116
Address $ / SF SF Monthly Rent
Third Ave & East 49th Street $ 60
2,000
$ 10,000
E 52nd St & Lexington Avenue $ 64
2,400
$ 12,800
Madison Ave & East 55th Street $ 76
2,300
$ 14,566
Madison Ave & East 48th Street $ 70
1,800
$ 10,500
Fifth Ave & West 47th Street $ 74
1,900
$ 11,637
Avenue of the Americas & West 51th Street $ 84
2,200
$ 15,400
Rockefeller Plz & West 50th Street $ 92
1,600
$ 12,266
Park Ave & East 56th Street $ 98
1,900
$ 15,516
Fifth Ave & West 55th Street West 56th Street $ 165
2,300
$ 31,625
Address $ / SF SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 49
15,700
$ 64,108
Park Ave & East 125th Street $ 49
9,000
$ 36,750
W 125th St & Between Malcolm X Blvd $ 53
13,700
$ 60,508
W 125th St & Frederick Douglass Boulevard $ 53
22,500
$ 99,375
Address $ / SF SF Monthly Rent
3rd Ave & Between East 90th Street $ 74
2,700
$ 16,650
Park Ave & East 125th Street $ 49
3,700
$ 15,108
W 125th St & Between Malcolm X Blvd $ 55
4,300
$ 19,708
Address $ / SF SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 48
2,000
$ 8,000
Address $ / SF SF Monthly Rent
E 124th St & Park Avenue $ 48
9,200
$ 37,183
Address $ / SF SF Monthly Rent
W 161st St & Broadway $ 32
5,000
$ 13,125
Address $ / SF SF Monthly Rent
W 47th St & Avenue of the Americas $ 54
2,000
$ 8,916

Retail Spaces for Rent at 450 W 126th St

Rent Retail 450 W 126th St

Rent Medical Space at 450 W 126th St

$ / SF SF Monthly Rent
Please notify me when a new space is available
Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 450 West 126th Street. This trend is projected to continue. Opportunities for subleases remain available at 450 West 126th Street and in the nearby Upper East Side neighborhood.
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450 West 126th Street nyc
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450 West 126th Street Property Overview

Building Address: 450 W 126th St, New York NY 10027
Building Name: Taystee Building
Building Alternate Address: 450 W 126th St
Zip Code:10027
Neighborhood:Upper East Side
Borough:Manhattan
Stories:11
Year Built:
Building Class:A
Block & lot:01966-0095

The Taystee Lab Building, located at 450 West 126th Street in Manhattanville, West Harlem, is a significant development in the area. It is named after the Taystee Cake Bakery Factory that once occupied the site. The building is part of the Manhattanville Factory District, a master-planned neighborhood stretching from West 125th to West 128th Streets.

Developed by Janus Property Group and designed by LEVENBETTS and SLCE, the 11-story structure offers 350,000 square feet of space. It features Class A office space, state-of-the-art lab facilities, and areas for life sciences, technology, academia, non-profit, retail, and the arts.

The building topped out in January 2020 and was completed by the end of 2021. It includes flexible floor plans with 14-foot-high ceilings and 20,000 square feet of outdoor space, including a landscaped courtyard and private terraces.

The Taystee Lab Building is LEED-certified and equipped with high-capacity power systems, making it suitable for life science and innovative manufacturing. It serves as a key component in the revitalization of West Harlem, supporting the growth of New York City's life sciences industry.

450 W 126th St, Manhattan, NYC

Also known as:

  • Taystee Labs
  • Manhattanville Office Property

Location Highlights:

  • Near Riverside Park and Harlem Piers
  • Close to Columbia University and City College
  • Accessible via A, B, C, D, and 1 subway lines

  • 24 Hour Access
  • Bio-Tech/Lab Space
  • Bus Line
  • Controlled Access
  • Concierge
  • Metro/Subway
  • Roof Terrace
  • Bicycle Storage
  • High Ceilings
  • Natural Light
  • Air Conditioning
  • Balcony
  • Private Landscaped Courtyard
  • Outdoor Terraces

450 West 126th Street, located in the Harlem/North Manhattan neighborhood of Manhattan, is a prominent office building known as the Taystee Building. It offers a mix of office and R&D spaces, totaling approximately 341,561 square feet. The building is a Class A property, constructed in 2021, and features amenities such as high ceilings, natural light, air conditioning, and a roof terrace.

The area benefits from excellent transportation links, including the A, B, C, and D subway lines nearby, as well as proximity to Columbia University and City College. The building is part of the revitalized Manhattanville Factory District, which has become a hub for commercial businesses and educational institutions.


Internet Providers Available at 450 W 126th St, Manhattan, NYC:

  • Verizon Fios: Known for high speeds up to 2.3 Gbps, reliable service, and competitive pricing starting at $49.99.
  • Astound Broadband Powered by RCN: Offers cable and fiber services with unlimited data, speeds up to 1.5 Gbps, and low prices starting at $20.
  • Spectrum: Provides widespread coverage with speeds up to 1 Gbps and competitive pricing starting at $50.

Location: 450 W 126th St, Manhattan, NYC 10027

Transportation:

  • Bus: M10, M101, M11, M125, M2, M60-SBS
  • Train: Harlem, Hudson
  • Subway: 2, A, C, D, B

Nearest Subway Station: 125 St (4 min walk)

Nearest Bus Stops:

  • Frederick Douglass Blvd/W 125 St (2 min walk)
  • W 125 St/Frederick Douglass Blvd (3 min walk)
  • Saint Nicholas Av/W 125 St (4 min walk)

Cross Streets: Frederick Douglass Blvd, Saint Nicholas Ave


Finnerty Economic Consulting, LLC. Testimonial

Finnerty Economic Consulting, LLC. testimonial To Whom It May Concern: My firm engaged Optimal Spaces when I searched for professional office space in New York City in 2005 and again in 2012 when the first lease expired and we decided to look for better office space in midtown Manhattan. I leased office space at 60 East 42"d Street in 2005 and office space at 122 East 42"d Street in 2012 with Stephen's assistance. When I sold my business to AlixPartners in 2014, I recommended that AlixPartners retain Optimal Spaces to negotiate a termination ofthe lease at 122 East 42"d Street. I worked very closely with Stephen Sunderland, Senior Managing Director of Optimal Spaces, during both searches for office space as well as during the lease termination process. Stephen is very knowledgeable regarding the Manhattan office market. His advice proved crucial in negotiating two leases and securing the lease termination on favorable terms. He made himself available on short notice to view properties, and he identified a range of lease opportunities in various locations at different price points. I was able to benefit from his expertise to find suitable space without extensive searching. I would not hesitate to recommend Stephen Sunderland and his firm to anyone who is searching for office space in Manhattan. Very truly yours, John D. Finnerty Managing Principal
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Tenant Representation: Optimal Spaces acts exclusively as a "Tenant Broker," only representing tenants, never landlords.
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Cost Savings: They negotiate rental price and identify/abate "hidden costs."

Why Optimal Spaces –
Tenant Broker

✓
  • No fee for clients renting space.
  • We work for YOU, not the landlord.
  • Save 15–20% on your business costs.
  • Save 100–200 hours of research.
  • Access to all available spaces.
  • Specialized real estate expertise.

Alone or with other broker

✕
  • Miss deals and hard-to-find spaces.
  • Potential conflict of interest (often represent landlords).
  • Only 10% of available spaces are online.
  • Lack of specialized expertise.
  • May not get the best terms or uncover hidden costs.
Why Use a Tenant Broker: Your Advocate in Commercial Real Estate
1. The Crucial Distinction: Whose Side Are They On?
2. It Almost Always Costs You Nothing
3. Access to “Hidden” Inventory
4. Negotiating Beyond Base Rent
5. Time Savings & Process Management
6. Mitigating Risk (the “Gotchas”)
Summary: Don’t rely on the landlord’s agent. A tenant broker is your advocate, provides better data, negotiates a complete package, and typically costs you nothing.

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