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Rent/Lease Office 450 W 126th St

Lease Office 450 W 126th St

$ / SF / Yr SF Monthly Rent
Negotiable

Rent Sublease Office at 450 W 126th St

Nearby Sublease office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
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Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person
Interior office/person
Team Rooms
Suites

Nearby office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
W 125th St & Adam Clayton Powell Jr. Boulevard $ 96
20,400
$ 163,200
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 48.5
15,700
$ 63,454
W 125th St & Between Malcolm X Blvd $ 55
13,700
$ 62,791
W 125th St & Frederick Douglass Boulevard $ 55
22,500
$ 103,125
Address $ / SF / Yr SF Monthly Rent
W 125th St & Between Malcolm X Blvd $ 54
4,300
$ 19,350
Address $ / SF / Yr SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 47.5
2,000
$ 7,916
Address $ / SF / Yr SF Monthly Rent
Park Ave & East 130th Street $ 31.5
9,000
$ 23,625
Riverside Dr & West 119th Street $ 30
9,800
$ 24,500
Address $ / SF / Yr SF Monthly Rent
Park Ave & East 130th Street $ 23
6,500
$ 12,458
Riverside Dr & West 119th Street $ 28
2,700
$ 6,300
Address $ / SF / Yr SF Monthly Rent
Park Ave & East 130th Street $ 26
1,600
$ 3,466
Riverside Dr & West 119th Street $ 25.78
1,600
$ 3,437

Retail Spaces for Rent at 450 W 126th St

Nearby Office Tenants Leased
  • Roberta Washington Architects leased 1,413 SF at 68 East 131st St
  • New York State Office of… leased 51,659 SF at 55 West 125th St
  • Gagosian Gallery leased 50,000 SF at 980 Madison Ave
  • New York State Workers' Compensation Board leased 45,205 SF at 215 West 125th St
  • Beth Israel Medical Center leased 38,461 SF at 1825 Park Ave
  • CareMax leased 27,400 SF at 1915 Third Ave
  • Avantus Renal Therapy U… leased 19,906 SF at 315 East 62nd St
  • Icahn School of Medicine leased 12,000 SF at 207 East 94th Street
  • Volastra Therapeutics leased 11,000 SF at 1361 Amsterdam Avenue
  • The Studio Museum of Ha… leased 10,000 SF at 310 Lenox Ave
Nearby Retail Tenants Leased
  • Wells Fargo leased 6,882 SF at 286 Lenox Avenue
  • Long's Bedding & Interiors leased 6,165 SF at 1220 Third Avenue
  • Ricky's NYC leased 5,180 SF at 55 West 125th St
  • Rebecca Taylor leased 4,338 SF at 980 Madison Ave
  • Galaxy Medical PC leased 4,239 SF at 68 East 131st St
  • Hammacher Schlemmer leased 4,143 SF at 145 East 57th St
  • Swerve Fitness leased 3,500 SF at 1140 Third Avenue
  • The House of Little People leased 2,800 SF at 401 East 84th St
  • Envy Corp. leased 2,500 SF at 4261 Broadway
  • City Mall leased 2,500 SF at 4-14 West 125th Street
$ / SF SF Monthly Rent
Please notify me when a new space is available
Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 450 West 126th Street. This trend is projected to continue. Opportunities for subleases remain available at 450 West 126th Street and in the nearby Harlem neighborhood.
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450 West 126th Street nyc
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Why Optimal Spaces Tenant Broker

  • Lease negotiation: full terms, renewals, expansion options
  • Cost analysis, inventory identification, negotiating scope
  • Risk mitigation against hidden pitfalls

Cost Savings

  • Negotiate 30+ leasing points to prevent hidden costs
  • Save 10–15% on total leasing costs
  • Save 100–200 hours filtering unviable spaces
  • Property access via broker databases and networks (off-market, subleases, future availability)

Alone or With Other Brokers

  • Managing agents owe fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
  • Inherent conflict of interest as most brokers represent landlords
  • Risk of weaker terms and overlooked hidden costs
  • Heavy workload falls on you while best spaces are missed

450 West 126th Street Property Overview

Building Address: 450 W 126th St, New York NY 10027
Building Name: Taystee Building
Building Alternate Address: 450 W 126th St
Zip Code:10027
Neighborhood:Harlem
Borough:Manhattan
Stories:11
Year Built:
Building Class:A
Block & lot:01966-0095

The Taystee Lab Building, located at 450 West 126th Street in Manhattanville, West Harlem, is a significant development in the area. It is named after the Taystee Cake Bakery Factory that once occupied the site. The building is part of the Manhattanville Factory District, a master-planned neighborhood stretching from West 125th to West 128th Streets.

Developed by Janus Property Group and designed by LEVENBETTS and SLCE, the 11-story structure offers 350,000 square feet of space. It features Class A office space, state-of-the-art lab facilities, and areas for life sciences, technology, academia, non-profit, retail, and the arts.

The building topped out in January 2020 and was completed by the end of 2021. It includes flexible floor plans with 14-foot-high ceilings and 20,000 square feet of outdoor space, including a landscaped courtyard and private terraces.

The Taystee Lab Building is LEED-certified and equipped with high-capacity power systems, making it suitable for life science and innovative manufacturing. It serves as a key component in the revitalization of West Harlem, supporting the growth of New York City's life sciences industry.

450 W 126th St, Manhattan, NYC

Also known as:

  • Taystee Labs
  • Manhattanville Office Property

Location Highlights:

  • Near Riverside Park and Harlem Piers
  • Close to Columbia University and City College
  • Accessible via A, B, C, D, and 1 subway lines

  • 24 Hour Access
  • Bio-Tech/Lab Space
  • Bus Line
  • Controlled Access
  • Concierge
  • Metro/Subway
  • Roof Terrace
  • Bicycle Storage
  • High Ceilings
  • Natural Light
  • Air Conditioning
  • Balcony
  • Private Landscaped Courtyard
  • Outdoor Terraces

450 West 126th Street, located in the Harlem/North Manhattan neighborhood of Manhattan, is a prominent office building known as the Taystee Building. It offers a mix of office and R&D spaces, totaling approximately 341,561 square feet. The building is a Class A property, constructed in 2021, and features amenities such as high ceilings, natural light, air conditioning, and a roof terrace.

The area benefits from excellent transportation links, including the A, B, C, and D subway lines nearby, as well as proximity to Columbia University and City College. The building is part of the revitalized Manhattanville Factory District, which has become a hub for commercial businesses and educational institutions.


Internet Providers Available at 450 W 126th St, Manhattan, NYC:

  • Verizon Fios: Known for high speeds up to 2.3 Gbps, reliable service, and competitive pricing starting at $49.99.
  • Astound Broadband Powered by RCN: Offers cable and fiber services with unlimited data, speeds up to 1.5 Gbps, and low prices starting at $20.
  • Spectrum: Provides widespread coverage with speeds up to 1 Gbps and competitive pricing starting at $50.

Location: 450 W 126th St, Manhattan, NYC 10027

Transportation:

  • Bus: M10, M101, M11, M125, M2, M60-SBS
  • Train: Harlem, Hudson
  • Subway: 2, A, C, D, B

Nearest Subway Station: 125 St (4 min walk)

Nearest Bus Stops:

  • Frederick Douglass Blvd/W 125 St (2 min walk)
  • W 125 St/Frederick Douglass Blvd (3 min walk)
  • Saint Nicholas Av/W 125 St (4 min walk)

Cross Streets: Frederick Douglass Blvd, Saint Nicholas Ave

Nearby Office Tenants Leased
  • Roberta Washington Architects leased 1,413 SF at 68 East 131st St
  • New York State Office of… leased 51,659 SF at 55 West 125th St
  • Gagosian Gallery leased 50,000 SF at 980 Madison Ave
  • New York State Workers' Compensation Board leased 45,205 SF at 215 West 125th St
  • Beth Israel Medical Center leased 38,461 SF at 1825 Park Ave
  • CareMax leased 27,400 SF at 1915 Third Ave
  • Avantus Renal Therapy U… leased 19,906 SF at 315 East 62nd St
  • Icahn School of Medicine leased 12,000 SF at 207 East 94th Street
  • Volastra Therapeutics leased 11,000 SF at 1361 Amsterdam Avenue
  • The Studio Museum of Ha… leased 10,000 SF at 310 Lenox Ave
Nearby Retail Tenants Leased
  • Wells Fargo leased 6,882 SF at 286 Lenox Avenue
  • Long's Bedding & Interiors leased 6,165 SF at 1220 Third Avenue
  • Ricky's NYC leased 5,180 SF at 55 West 125th St
  • Rebecca Taylor leased 4,338 SF at 980 Madison Ave
  • Galaxy Medical PC leased 4,239 SF at 68 East 131st St
  • Hammacher Schlemmer leased 4,143 SF at 145 East 57th St
  • Swerve Fitness leased 3,500 SF at 1140 Third Avenue
  • The House of Little People leased 2,800 SF at 401 East 84th St
  • Envy Corp. leased 2,500 SF at 4261 Broadway
  • City Mall leased 2,500 SF at 4-14 West 125th Street

VSA Consulting Group Testimonial

VSA Consulting Group testimonial To whom it may concern: I am writing to recommend Stephen Sunderland and Optimal Spaces Inc. for the excellent job they did in finding us a lease at our new space. They were fast and effecient in locating spaces that met our needs and corporate image, aggressive in negotiating on our behalf, and effective in communicating our needs to the landlord and getting our offer accepted. I look forward to working with the team at Optimal Spaces Inc. again. Very truly yours, Jack Sichterman Partner/Managing Director
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