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Rent/Lease Office 235 E 42nd St

Lease Office 235 E 42nd St

Rent Sublease Office at 235 E 42nd St

Nearby Sublease office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
Fifth Ave & East 44th Street $ 65
13,500
$ 73,125
E 42nd St & Lexington Avenue $ 40
55,700
$ 185,666
5th Ave & East 44th Street $ 70.5
9,600
$ 56,400
Park Ave & East 45th Street $ 98
9,700
$ 79,216
Third Ave & East 39th Street $ 35
49,100
$ 143,208
Lexington Ave & East 43rd Street $ 55
12,900
$ 59,125
Address $ / SF / Yr SF Monthly Rent
Park Ave & East 40th Street $ 66
4,300
$ 23,650
Lexington Ave & East 41st Street $ 63
3,800
$ 19,950
5th Ave & East 44th Street $ 71
7,000
$ 41,416
E 42nd St & Lexington Avenue $ 49
4,800
$ 19,600
Park Ave & East 39th Street $ 99
4,200
$ 34,650
Fifth Ave & East 44th Street $ 50
3,300
$ 13,750
Address $ / SF / Yr SF Monthly Rent
Fifth Ave & East 45th Street $ 50
2,100
$ 8,750
Park Ave & East 40th Street $ 67.5
2,000
$ 11,250
Address $ / SF / Yr SF Monthly Rent
Lexington Ave & East 41st Street $ 24.75
7,300
$ 15,056
Fifth Ave & East 45th Street $ 40
10,300
$ 34,333
Address $ / SF / Yr SF Monthly Rent
Madison Ave & East 40th Street $ 58.75
4,200
$ 20,562
Fifth Ave & East 45th Street $ 54
3,400
$ 15,300
Lexington Ave & East 41st Street $ 27.25
5,600
$ 12,716
E 42nd St & Park Avenue $ 42
5,100
$ 17,850
E 42nd St & Lexington Avenue $ 52
4,800
$ 20,800
Fifth Ave & East 44th Street $ 51.5
3,300
$ 14,162
E 41st St & Fifth Avenue $ 47
2,700
$ 10,575
Address $ / SF / Yr SF Monthly Rent
Fifth Ave & East 45th Street $ 51.5
2,100
$ 9,012
Lexington Ave & East 40th Street $ 41
2,100
$ 7,175
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person
Interior office/person
Team Rooms
Suites

Nearby office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
E 40th St & Fifth Avenue $ 70
8,100
$ 47,250
Park Ave & East 41st Street $ 175
12,200
$ 177,916
Third Ave & East 46th Street $ 81
12,100
$ 81,675
Fifth Ave & East 40th Street $ 85
11,200
$ 79,333
Address $ / SF / Yr SF Monthly Rent
E 40th St & Fifth Avenue $ 70
6,400
$ 37,333
Third Ave & East 46th Street $ 62
4,100
$ 21,183
Vanderbilt Ave & East 44th Street $ 49
5,300
$ 21,641
Third Ave & East 40th Street $ 63
3,600
$ 18,900
Address $ / SF / Yr SF Monthly Rent
Lexington Ave & East 41st Street $ 57
1,500
$ 7,125
E 44th St & Lexington Avenue $ 82
2,300
$ 15,716
Lexington Ave & East 42nd Street $ 61
1,500
$ 7,625
Third Ave & East 41st Street $ 55
1,700
$ 7,791
Park Ave & East 41st Street $ 85
2,300
$ 16,291
Address $ / SF / Yr SF Monthly Rent
Madison Ave & East 40th Street $ 65.5
14,600
$ 79,691
Vanderbilt Ave & East 44th Street $ 79
8,100
$ 53,325
E 42nd St & Park Avenue $ 59
9,700
$ 47,691
Fifth Ave & East 42nd Street $ 58
7,400
$ 35,766
E 44th St & Third Avenue $ 58
8,400
$ 40,600
Fifth Ave & East 45th Street $ 68
7,900
$ 44,766
Address $ / SF / Yr SF Monthly Rent
Madison Ave & East 41st Street $ 56
5,700
$ 26,600
Madison Ave & East 40th Street $ 75
3,600
$ 22,500
Vanderbilt Ave & East 44th Street $ 50
4,000
$ 16,666
Second Ave & East 43rd Street $ 56
4,800
$ 22,400
Madison Ave & East 39th Street $ 50
2,700
$ 11,250
Lexington Ave & East 41st Street $ 60
3,700
$ 18,500
E 42nd St & Park Avenue $ 66
6,700
$ 36,850
Fifth Ave & East 42nd Street $ 60
3,800
$ 19,000
Madison Ave & East 40th Street $ 45
3,500
$ 13,125
E 44th St & Third Avenue $ 48
4,500
$ 18,000
Madison Ave & East 40th Street $ 55
2,500
$ 11,458
Address $ / SF / Yr SF Monthly Rent
Madison Ave & East 40th Street $ 67
1,700
$ 9,491
Second Ave & East 43rd Street $ 59
2,300
$ 11,308
Madison Ave & East 39th Street $ 52
1,900
$ 8,233
Fifth Ave & East 42nd Street $ 60
1,600
$ 8,000
Madison Ave & East 40th Street $ 60
2,400
$ 12,000
Madison Ave & East 41st Street $ 55
2,000
$ 9,166
E 42nd St & Madison Avenue $ 69
2,100
$ 12,075
E 42nd St & Lexington Avenue $ 61
2,200
$ 11,183
E 44th St & Fifth Avenue $ 55
2,200
$ 10,083
Address $ / SF / Yr SF Monthly Rent
Fifth Ave & East 39th Street $ 52
7,300
$ 31,633
E 39th St & Fifth Avenue $ 39.5
7,900
$ 26,004
Fifth Ave & Between East 42nd Street $ 84
9,200
$ 64,400
Address $ / SF / Yr SF Monthly Rent
E 40th St & Lexington Avenue $ 48.5
3,000
$ 12,125
Fifth Ave & Between East 42nd Street $ 83.5
6,000
$ 41,750
Address $ / SF / Yr SF Monthly Rent
E 40th St & Lexington Avenue $ 50.5
1,600
$ 6,733

Retail Spaces for Rent at 235 E 42nd St

Nearby Office Tenants Leased
  • Ziff Brothers Investment leased 125,000 SF at 350 Park Avenue
  • Mitsubishi International Corp. leased 122,500 SF at 655 Third Ave
  • BDO Seidman leased 121,441 SF at 100 Park Ave
  • The United Nations leased 120,000 SF at 730 Third Ave
  • Convene leased 116,000 SF at 530 Fifth Avenue
  • McLaughlin & Stern leased 112,000 SF at 260 Madison Avenue
  • TBWA Worldwide leased 107,308 SF at 488 Madison Ave
  • KPMG LLP leased 102,979 SF at 560 Lexington Ave
  • Crain Communications leased 100,000 SF at 711 Third Ave
  • Pernod Ricard USA, Inc. leased 97,444 SF at 250 Park Ave
Nearby Retail Tenants Leased
  • Sephora leased 5,316 SF at 300 Madison Avenue
  • Wells Fargo leased 4,700 SF at 535 Madison Avenue
  • Joseph Abboud leased 4,600 SF at 424 Madison Ave
  • Daum Inc.; Haviland Inc. leased 4,500 SF at 499 Park Ave
  • Wells Fargo leased 4,328 SF at 437 Madison Avenue
  • MedRite leased 4,200 SF at 330 West 42nd St
  • FILA leased 4,087 SF at 340 Madison Ave
  • RFR Realty leased 4,066 SF at 275 Madison Avenue
  • Pret A Manger leased 3,889 SF at 1071 Avenue of the Americas
  • CTSH LLC Deli leased 3,800 SF at 633 Third Ave
$ / SF SF Monthly Rent
Please notify me when a new space is available
Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 235 East 42nd Street. This trend is projected to continue. Opportunities for subleases remain available at 235 East 42nd Street and in the nearby Grand Central neighborhood.
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235 East 42nd Street nyc
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Why Optimal Spaces Tenant Broker

  • Lease negotiation: full terms, renewals, expansion options
  • Cost analysis, inventory identification, negotiating scope
  • Risk mitigation against hidden pitfalls

Cost Savings

  • Negotiate 30+ leasing points to prevent hidden costs
  • Save 10–15% on total leasing costs
  • Save 100–200 hours filtering unviable spaces
  • Property access via broker databases and networks (off-market, subleases, future availability)

Alone or With Other Brokers

  • Managing agents owe fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
  • Inherent conflict of interest as most brokers represent landlords
  • Risk of weaker terms and overlooked hidden costs
  • Heavy workload falls on you while best spaces are missed

235 East 42nd Street Property Overview

Building Address: 235 E 42nd St, New York NY 10017
Building Name: Pfizer World Headquarters
Building Alternate Address: 235 E 42nd St
Zip Code:10017
Neighborhood:Grand Central
Borough:Manhattan
Stories:33
Year Built:1961
Building Class:A

235 East 42nd Street, formerly part of Pfizer's presence in New York, is a significant building in Manhattan's Midtown area. Built in 1960, it served as Pfizer's World Headquarters until the company moved to the Spiral near Hudson Yards in 2023.

The building is currently undergoing a major redevelopment. It is being converted into a residential property as part of the largest office-to-residential conversion in New York City's history. The project involves transforming the 33-story building into a market-rate multifamily complex with about 910 units, along with retail and amenity spaces.

This conversion is part of a larger project that includes an adjacent building at 219 East 42nd Street. Together, these buildings will offer over 1,600 residential units, significantly contributing to the transformation of Midtown East into a vibrant mixed-use district.

Pfizer World Headquarters is located at 235 East 42nd Street, New York, NY 10017. Alternate addresses for this property include:

  • 785-791 2nd Ave, New York, NY 10017
  • 229-241 E 42nd St, New York, NY 10017
  • 228-238 E 43rd St, New York, NY 10017

The residential complex at 235 E 42nd St offers a range of amenities, including:

  • Rooftop pool
  • Fitness center
  • Ground floor retail
  • Offices
  • Over 100,000 square feet of amenity space

235 East 42nd Street, formerly the Pfizer World Headquarters, is a 33-story office building located in Manhattan, NYC. While specific current tenants are not detailed, nearby office tenants include Crain Communications and Salesforce.com.


Internet providers available at 235 E 42nd St, Manhattan, NYC include:

  • Verizon: Offers high-speed Fios service with speeds up to 2.3 Gbps.
  • Spectrum: Provides cable and fiber services with speeds up to 1 Gbps.
  • Astound Broadband Powered by RCN: Offers both cable and fiber services with speeds up to 1.5 Gbps.
  • Earthlink: Provides fiber service with speeds up to 2,300 Mbps.

Pfizer is located at 235 E 42nd St, Manhattan, NYC.

Nearest Public Transit:

  • Bus Stops: E 42nd St and 2nd Ave, 2 Av/E 42 St, E 42 St/2 Av (1 min walk)
  • Subway Station: Grand Central-42 St (3 min walk)
  • Train Station: Grand Central Madison (3 min walk), Grand Central (6 min walk)
  • Ferry Station: East 34th Street (14 min walk)

Cross Streets: 2nd Avenue and 3rd Avenue

Nearby Office Tenants Leased
  • Ziff Brothers Investment leased 125,000 SF at 350 Park Avenue
  • Mitsubishi International Corp. leased 122,500 SF at 655 Third Ave
  • BDO Seidman leased 121,441 SF at 100 Park Ave
  • The United Nations leased 120,000 SF at 730 Third Ave
  • Convene leased 116,000 SF at 530 Fifth Avenue
  • McLaughlin & Stern leased 112,000 SF at 260 Madison Avenue
  • TBWA Worldwide leased 107,308 SF at 488 Madison Ave
  • KPMG LLP leased 102,979 SF at 560 Lexington Ave
  • Crain Communications leased 100,000 SF at 711 Third Ave
  • Pernod Ricard USA, Inc. leased 97,444 SF at 250 Park Ave
Nearby Retail Tenants Leased
  • Sephora leased 5,316 SF at 300 Madison Avenue
  • Wells Fargo leased 4,700 SF at 535 Madison Avenue
  • Joseph Abboud leased 4,600 SF at 424 Madison Ave
  • Daum Inc.; Haviland Inc. leased 4,500 SF at 499 Park Ave
  • Wells Fargo leased 4,328 SF at 437 Madison Avenue
  • MedRite leased 4,200 SF at 330 West 42nd St
  • FILA leased 4,087 SF at 340 Madison Ave
  • RFR Realty leased 4,066 SF at 275 Madison Avenue
  • Pret A Manger leased 3,889 SF at 1071 Avenue of the Americas
  • CTSH LLC Deli leased 3,800 SF at 633 Third Ave

Recent News About 235 East 42nd Street

Vaultus Professional Service Testimonial

Vaultus Professional Service testimonial To whom it may concern: I have had the opportunity to work with "Optimal Spaces" (specifically, Stephen Sunderland) over the last 18 months. Steve was hired to find a reasonably priced lease for corporate office space that would support our highly professional environment. I considered this to be a significant challenge since Manhattan was experiencing a severe shortage in available professional spaces. Honestly, I was expecting to be "sold" a space that would not meet all of our needs. However, in a short period of time, Stephen found a tower-floor space that exceeded my expectations and that was approximately 25% below the current market rates for comparable space. The most important aspect of working with Stephen is the level to which I can trust him to act in my best interest. I believe that Stephen possesses extensive knowledge of the real estate market and negotiation, is responsive, and performs his work in a highly professional manner. I am impressed by Stephen's sincere desire to understand his clients' needs. It is clear to me that Stephen is most interested in building mutually beneficial business relationships with his clients -- not the commissions they represent. I am happy to recommend "Optimal Spaces" to other growing businesses, and I look forward to working with "Optimal Spaces" again. Sincerely, Joseph J. Tutrone Vice President Vaultus Professional Service
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