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Rent Office 235 East 42nd Street

Lease Office 235 E 42nd St

$ / SF SF Monthly Rent
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$ / SF SF Monthly Rent
$ / SF SF Monthly Rent

Nearby Sublease office Spaces for Rent

Address $ / SF SF Monthly Rent
Fifth Ave & East 44th Street $ 65
13,500
$ 73,125
Address $ / SF SF Monthly Rent
E 42nd St & Lexington Avenue $ 49
4,800
$ 19,600
Park Ave & East 39th Street $ 99
4,200
$ 34,650
Fifth Ave & East 44th Street $ 50
3,300
$ 13,750
Address $ / SF SF Monthly Rent
Fifth Ave & East 45th Street $ 50
2,100
$ 8,750
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Madison Ave & East 40th Street $ 57
4,200
$ 20,037
Lexington Ave & East 41st Street $ 25
5,600
$ 11,783
E 42nd St & Park Avenue $ 42
5,100
$ 17,850
E 42nd St & Lexington Avenue $ 50
4,800
$ 20,000
Fifth Ave & East 44th Street $ 52
3,300
$ 14,162
Address $ / SF SF Monthly Rent
Fifth Ave & East 45th Street $ 52
2,100
$ 9,012
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person $ 2621 $ 1300 $ 775
Interior office/person $ 1871 $ 800 $ 525
Team Rooms $ 10621 $ 8050 $ 5025
Suites $ 20621 $ 12050 $ 7025

Nearby office Spaces for Rent

Address $ / SF SF Monthly Rent
E 40th St & Fifth Avenue $ 70
8,100
$ 47,250
Park Ave & East 41st Avenue $ 175
12,200
$ 177,916
Third Ave & East 46th Street $ 81
12,100
$ 81,675
Fifth Ave & East 40th Street $ 85
11,200
$ 79,333
Third Ave & East 40th Street $ 60
27,700
$ 138,500
Address $ / SF SF Monthly Rent
E 40th St & Fifth Avenue $ 70
6,400
$ 37,333
Third Ave & East 46th Street $ 62
4,100
$ 21,183
Vanderbilt Ave & East 44th Street $ 49
5,300
$ 21,641
Third Ave & East 39th Street $ 70
4,700
$ 27,416
Address $ / SF SF Monthly Rent
Lexington Ave & East 41st Street $ 57
1,500
$ 7,125
E 44th St & East 44th Street $ 82
2,300
$ 15,716
E 45th St & Lexington Avenue $ 75
2,400
$ 15,000
Lexington Ave & East 42nd Street $ 61
1,500
$ 7,625
Third Ave & East 41st Street $ 55
1,700
$ 7,791
Park Ave & East 41st Street $ 85
2,300
$ 16,291
Address $ / SF SF Monthly Rent
Madison Ave & East 40th Street $ 66
14,600
$ 79,691
Vanderbilt Ave & East 44th Street $ 81
8,100
$ 54,675
E 42nd St & Park Avenue $ 59
9,700
$ 47,691
Fifth Ave & East 42nd Street $ 58
7,400
$ 35,766
Fifth Ave & East 45th Street $ 68
7,900
$ 44,766
E 42nd St & Lexington Avenue $ 64
8,400
$ 45,150
Address $ / SF SF Monthly Rent
Madison Ave & East 41st Avenue $ 56
5,700
$ 26,837
Madison Ave & East 40th Street $ 76
3,600
$ 22,650
Vanderbilt Ave & East 44th Street $ 50
4,000
$ 16,833
Madison Ave & East 39th Street $ 50
2,700
$ 11,362
Lexington Ave & East 41st Street $ 60
3,700
$ 18,654
E 42nd St & Park Avenue $ 66
6,700
$ 36,850
E 44th St & Third Avenue $ 48
4,500
$ 18,000
Madison Ave & East 40th Street $ 75
3,900
$ 24,375
Fifth Ave & East 45th Street $ 84
6,800
$ 47,600
E 45th St & Fifth Avenue $ 55
3,800
$ 17,416
Madison Ave & East 40th Street $ 56
6,900
$ 32,200
Madison Ave & East 41st Avenue $ 62
2,600
$ 13,325
Third Ave & Between East 44th Street $ 66
4,800
$ 26,600
E 42nd St & Madison Avenue $ 70
4,900
$ 28,583
Address $ / SF SF Monthly Rent
Madison Ave & East 40th Street $ 66
1,700
$ 9,279
Second Ave & East 43rd Street $ 58
2,300
$ 11,020
Madison Ave & East 39th Street $ 50
1,900
$ 7,995
Fifth Ave & East 42nd Street $ 60
1,600
$ 8,000
Madison Ave & East 41st Avenue $ 55
2,000
$ 9,166
E 42nd St & Madison Avenue $ 70
2,100
$ 12,250
E 42nd St & Lexington Avenue $ 60
2,200
$ 10,908
E 44th St & Fifth Avenue $ 55
2,200
$ 10,083
Lexington Ave & East 44th Street $ 55
1,500
$ 6,875
Address $ / SF SF Monthly Rent
Fifth Ave & East 39th Street $ 52
7,300
$ 31,633
E 39th St & Fifth Avenue $ 39
7,900
$ 25,675
Fifth Ave & Between East 42nd Street $ 84
9,200
$ 64,016
Address $ / SF SF Monthly Rent
E 40th St & Lexington Avenue $ 49
3,000
$ 12,250
Fifth Ave & Between East 42nd Street $ 84
6,000
$ 42,000
Address $ / SF SF Monthly Rent
E 40th St & Lexington Avenue $ 49
1,600
$ 6,533

Retail Spaces for Rent at 235 E 42nd St

Rent Medical Space at 235 E 42nd St

Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 235 East 42nd Street. This trend is projected to continue. Opportunities for subleases remain available at 235 East 42nd Street and in the nearby Grand Central neighborhood.
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235 East 42nd Street nyc
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235 East 42nd Street Property Overview

Building Address: 235 E 42nd St, New York NY 10017
Building Name: Pfizer World Headquarters
Building Alternate Address: 235 E 42nd St
Zip Code:10017
Neighborhood:Grand Central
Borough:Manhattan
Stories:33
Year Built:1961
Building Class:A

235 East 42nd Street, formerly part of Pfizer's presence in New York, is a significant building in Manhattan's Midtown area. Built in 1960, it served as Pfizer's World Headquarters until the company moved to the Spiral near Hudson Yards in 2023.

The building is currently undergoing a major redevelopment. It is being converted into a residential property as part of the largest office-to-residential conversion in New York City's history. The project involves transforming the 33-story building into a market-rate multifamily complex with about 910 units, along with retail and amenity spaces.

This conversion is part of a larger project that includes an adjacent building at 219 East 42nd Street. Together, these buildings will offer over 1,600 residential units, significantly contributing to the transformation of Midtown East into a vibrant mixed-use district.

Pfizer World Headquarters is located at 235 East 42nd Street, New York, NY 10017. Alternate addresses for this property include:

  • 785-791 2nd Ave, New York, NY 10017
  • 229-241 E 42nd St, New York, NY 10017
  • 228-238 E 43rd St, New York, NY 10017

The residential complex at 235 E 42nd St offers a range of amenities, including:

  • Rooftop pool
  • Fitness center
  • Ground floor retail
  • Offices
  • Over 100,000 square feet of amenity space

235 East 42nd Street, formerly the Pfizer World Headquarters, is a 33-story office building located in Manhattan, NYC. While specific current tenants are not detailed, nearby office tenants include Crain Communications and Salesforce.com.


Internet providers available at 235 E 42nd St, Manhattan, NYC include:

  • Verizon: Offers high-speed Fios service with speeds up to 2.3 Gbps.
  • Spectrum: Provides cable and fiber services with speeds up to 1 Gbps.
  • Astound Broadband Powered by RCN: Offers both cable and fiber services with speeds up to 1.5 Gbps.
  • Earthlink: Provides fiber service with speeds up to 2,300 Mbps.

Pfizer is located at 235 E 42nd St, Manhattan, NYC.

Nearest Public Transit:

  • Bus Stops: E 42nd St and 2nd Ave, 2 Av/E 42 St, E 42 St/2 Av (1 min walk)
  • Subway Station: Grand Central-42 St (3 min walk)
  • Train Station: Grand Central Madison (3 min walk), Grand Central (6 min walk)
  • Ferry Station: East 34th Street (14 min walk)

Cross Streets: 2nd Avenue and 3rd Avenue


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Optimal Spaces can help you turn critical and complex real estate issues into opportunities for growth and or cost reduction. We offer the experience, know-how, and the strategic planning that helps lead to better decisions. Virtually everything you need to enhance the value of your business (for profit and not for profit) , you will find at Optimal Spaces.

About Optimal Spaces
Optimal Spaces are Tenant Brokers, only representing commercial tenants, not owners or landlords. By contrast, managing agents and most commercial brokers are "landlord agents" representing the interest of owners. Their goal is to market and lease their clients' properties with the best possible terms for the owners. Thus, they will neither show you as broad a selection nor push to get the best price, since their loyalty is to the Landlord. An Optimal Spaces agent will show you a broader range of properties and offer you a broader range of important services than a managing agent or commercial broker will. We will provide you with a market survey, floor plans, pricing expectations , and access to our rolodex: Optimal Spaces walks you through the process from start to finish. Upon entering your new space, it will look the way you want, all at the price you agreed to spend. In addition to negotiating the best price, we will reveal and abate many "hidden costs" to you. We will show you all the relevant available spaces and safeguard your interests throughout the process. Because of tour costs to provide these services, we ask in exchange that clients sign an Exclusive Brokerage Agreement. This allows us to plan appropriately for assisting you with every step of the process.

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