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Rent/Lease Office 2226 3rd Ave

Lease Office 2226 3rd Ave

$ / SF SF Monthly Rent
Negotiable
16,100
Negotiable
Please notify me when a new space is available
$ / SF SF Monthly Rent
$ / SF SF Monthly Rent

Nearby Sublease office Spaces for Rent

Address $ / SF SF Monthly Rent
W 57th St & Avenue of the Americas $ 112
25,000
$ 232,291
Avenue of the Americas & West 55th Street West 56th Street $ 62
7,300
$ 38,020
Madison Ave & East 54th Street $ 80
31,000
$ 206,666
Avenue Of The Americas & West 47th Street $ 58
10,000
$ 47,916
Park Ave & East 57th Street $ 160
10,800
$ 144,000
Madison Ave & East 59th Street $ 99
8,300
$ 68,475
Fifth Ave & West 52nd Street $ 130
10,300
$ 111,583
Address $ / SF SF Monthly Rent
Park Ave & East 54th Street $ 85
5,600
$ 39,666
Fifth Ave & East 56th Street $ 85
6,600
$ 46,750
Lexington Ave & East 50th Street $ 54
4,000
$ 18,000
Avenue of the Americas & West 55th Street West 56th Street $ 62
6,200
$ 32,033
Madison Ave & East 49th Street $ 69
5,500
$ 31,625
Address $ / SF SF Monthly Rent
Madison Ave & East 49th Street $ 76
2,200
$ 14,025
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
E 60th St & Madison Avenue $ 65
4,200
$ 22,750
W 57th St & Avenue of America $ 531
5,100
$ 225,675
Address $ / SF SF Monthly Rent
W 57th St & Avenue of America $ 531
2,300
$ 101,775
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Address $ / SF SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person $ 2781 $ 1300 $ 775
Interior office/person $ 2031 $ 800 $ 525
Team Rooms $ 10781 $ 8050 $ 5025
Suites $ 20781 $ 12050 $ 7025

Nearby office Spaces for Rent

Address $ / SF SF Monthly Rent
W 57th St & Avenue of the Americas $ 105
15,800
$ 138,250
Fifth Ave & East 55th Street $ 156
19,300
$ 251,704
Park Ave & East 58th Street $ 125
11,300
$ 117,708
Address $ / SF SF Monthly Rent
Third Ave & East 49th Street $ 50
4,300
$ 17,916
Park Ave & East 54th Street $ 80
3,500
$ 23,479
Park Ave & East 58th Street $ 125
4,000
$ 41,666
Third Ave & East 49th Street $ 73
3,800
$ 23,116
Madison Ave & East 55th Street $ 65
5,000
$ 27,083
Address $ / SF SF Monthly Rent
Third Ave & East 49th Street $ 60
2,000
$ 10,000
E 52nd St & Lexington Avenue $ 64
2,400
$ 12,800
Madison Ave & East 55th Street $ 76
2,300
$ 14,566
Madison Ave & East 48th Street $ 70
1,800
$ 10,500
Fifth Ave & West 47th Street $ 72
1,900
$ 11,479
Avenue of the Americas & West 51th Street $ 84
2,200
$ 15,400
Rockefeller Plz & West 50th Street $ 92
1,600
$ 12,266
Park Ave & East 56th Street $ 98
1,900
$ 15,516
Fifth Ave & West 55th Street West 56th Street $ 165
2,300
$ 31,625
Address $ / SF SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 48
15,700
$ 62,800
Park Ave & East 125th Street $ 49
9,000
$ 36,750
W 125th St & Between Malcolm X Blvd $ 54
13,700
$ 61,650
W 125th St & Frederick Douglass Boulevard $ 54
22,500
$ 101,250
Address $ / SF SF Monthly Rent
Park Ave & East 125th Street $ 49
3,700
$ 15,108
W 125th St & Between Malcolm X Blvd $ 55
4,300
$ 19,708
Address $ / SF SF Monthly Rent
Seventh Ave & Dr. Martin Luther King Jr. Boulevard $ 48
2,000
$ 7,916
Address $ / SF SF Monthly Rent
E 124th St & Park Avenue $ 48
9,200
$ 36,416
Address $ / SF SF Monthly Rent
W 161st St & Broadway $ 32
5,000
$ 13,125
Address $ / SF SF Monthly Rent
W 47th St & Avenue of the Americas $ 53
2,000
$ 8,833

Retail Spaces for Rent at 2226 3rd Ave

Rent Medical Space at 2226 3rd Ave

Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 2226 3rd Ave. This trend is projected to continue. Opportunities for subleases remain available at 2226 3rd Ave and in the nearby Upper East Side neighborhood.
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2226 3rd Ave nyc
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2226 3rd Ave Property Overview

Building Address: 2226 3rd Ave, New York NY 10035
Building Name: The Labs on 121
Zip Code:10035
Neighborhood:Upper East Side
Borough:Manhattan
Stories:11
Year Built:2023
Building Class:A

2226 3rd Avenue, located in East Harlem, Manhattan, NYC, is a ten-story mixed-use building that was completed in 2023. The structure stands 145 feet tall and offers 193,000 square feet of laboratory and medical research space, 36,547 square feet for commercial use, and 97,759 square feet of community facility space.

The building was designed by DXA Studio Architecture and developed by Real Estate Equities Corporation. It features a white corium masonry façade with a recessed grid of floor-to-ceiling windows framed by metal paneling. The design includes stepped setbacks on the upper levels of the southern and eastern elevations, topped with a flat parapet. A private 100-foot-long rear yard is also part of the property.

The project was facilitated by the city's LifeSci NYC initiative, which aims to invest $1 billion in developing the life sciences industry. Additionally, the 2017 rezoning of 60 East Harlem city blocks allowed for denser residential and commercial construction, enabling projects like 2226 3rd Avenue.

The building includes multiple green roofs and landscaped outdoor spaces. It is equipped with high ceiling heights, access to a loading dock, five elevators, and three generators. Nearby transportation options include the 4, 5, and 6 trains at the 125th Street station and the Metro-North Railroad at the Harlem-125th Street station.

2226 3rd Ave, Manhattan, NYC


2226 3rd Avenue, Manhattan, NYC offers several key building amenities:

  • 10-story mixed-use building with laboratory and medical research space
  • 193,000 square feet of lab space, 36,547 square feet for commercial use, and 97,759 square feet of community facility space
  • VIEW Smart Glass Windows
  • Three generators on the roof
  • Once-through ventilation with six to eight air changes per hour
  • Five elevators
  • Loading dock
  • Green roofs on the 6th floor setback and main roof areas
  • Private 100-foot-long rear yard

2226 3rd Avenue, Manhattan, NYC, is a 10-story office building with a total area of 133,426 square feet. It was built in 2022 and is located in the East Harlem neighborhood. The building is classified as an Office with Commercial 7-19 Stories (O6) and has a tax assessor's market value of $36,273,000.

As of the latest available information, there are no reported office tenants who have rented or leased space in this building. The property is currently seeking to attract tenants, particularly biotech startups and academic institutions, but no leases have been signed yet.

The building's proximity to key amenities and its modern construction make it an attractive location for potential tenants. However, specific details about current or past tenants are not available.


Internet Providers at 2226 3rd Ave, Manhattan, NYC:

  • Verizon Fios: Known for high speeds up to 2 Gbps and reliable service.
  • Astound Broadband Powered by RCN: Offers both cable and fiber services with unlimited data.
  • Spectrum: Provides cable internet with speeds up to 1 Gbps and widespread coverage.
  • STARRY Internet: Offers fixed wireless service with high customer satisfaction ratings.

2226 3rd Ave, Manhattan, NYC is located near several transportation options:

Bus Lines: M101, M103, M106, M15-SBS, M98

Subway Lines: 6, 4, 6X, N, Q

Train Lines: HARLEM, HUDSON, NEW HAVEN

Nearest Subway Station: 103 St (5-minute walk)

Nearest Bus Stops: E 106 St/3 Av, 3 Av/E 106 St (1-minute walk)

Cross Streets: East 106th Street and East 103rd Street


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Why Optimal Spaces –
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Alone or with other broker

  • Miss deals and hard-to-find spaces.
  • Potential conflict of interest (often represent landlords).
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  • Lack of specialized expertise.
  • May not get the best terms or uncover hidden costs.
Why Use a Tenant Broker: Your Advocate in Commercial Real Estate
1. The Crucial Distinction: Whose Side Are They On?
Landlord Rep (Listing Agent) — Fiduciary Duty: Landlord. Highest rent, best terms for landlord.
Tenant Rep (Tenant Broker) — Fiduciary Duty: Tenant Only. Lowest rent, best terms for tenant. Levels the playing field.
2. It Almost Always Costs You Nothing
3. Access to “Hidden” Inventory
4. Negotiating Beyond Base Rent
Landlord pays the broker fee — free expert representation for the tenant.
Access to hidden inventory: off-market listings, subleases, and future availabilities via broker databases and networks.
Negotiating beyond base rent: free rent, TI allowance, OPEX caps, and lease flexibility for renewal or expansion.
5. Time Savings & Process Management
6. Mitigating Risk (the “Gotchas”)
Tenant broker handles searching, scheduling, and RFPs — your outsourced real estate department with curated options and timeline management.
Mitigating risk: spotting pitfalls in LOI and lease such as restoration clauses and holdover penalties.
Summary: Don’t rely on the landlord’s agent. A tenant broker is your advocate, provides better data, negotiates a complete package, and typically costs you nothing.

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