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Rent/Lease Office 425 West 59th Street

Nearby Sublease office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
W 57th St & Seventh Avenue $ 59
10,800
$ 53,100
Broadway & West 51st Street $ 29
56,200
$ 135,816
W 57th St & Eighth Avenue $ 60
11,500
$ 57,500
Address $ / SF / Yr SF Monthly Rent
W 57th St & Eighth Avenue $ 39
5,000
$ 16,250
Address $ / SF / Yr SF Monthly Rent
Madison Ave & East 49th Street $ 76.5
2,200
$ 14,025
Address $ / SF / Yr SF Monthly Rent
W 54th St & Eighth Avenue $ 50
7,500
$ 31,250
Address $ / SF / Yr SF Monthly Rent
W 54th St & Eighth Avenue $ 51
4,300
$ 18,275
Address $ / SF / Yr SF Monthly Rent
W 57th St & Avenue of the Americas Negotiable
2,300
Negotiable
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Address $ / SF / Yr SF Monthly Rent
Type of Space Class A/month Class B/month Class C/month
Windowed office/person
Interior office/person
Team Rooms
Suites

Nearby office Spaces for Rent

Address $ / SF / Yr SF Monthly Rent
Columbus Cir & West 58th Street $ 87
13,000
$ 94,250
W 57th St & Seventh Avenue $ 97
10,900
$ 88,108
Broadway & West 53rd Street $ 71.5
10,800
$ 64,350
7th Ave & West 56th Street $ 105
9,200
$ 80,500
Address $ / SF / Yr SF Monthly Rent
W 57th St & Seventh Avenue $ 79
2,600
$ 17,116
Columbus Cir & West 58th Street $ 78.5
4,100
$ 26,820
Broadway & West 54th Street $ 95.5
5,700
$ 45,362
Broadway & West 53rd Street $ 49.5
3,300
$ 13,612
Broadway & West 57th Street $ 65
4,300
$ 23,291
7th Ave & West 56th Street $ 85
2,900
$ 20,541
W 56th St & Between Sixth Avenue $ 100.5
3,500
$ 29,312
Address $ / SF / Yr SF Monthly Rent
Broadway & West 57th Street $ 65
1,800
$ 9,750
Address $ / SF / Yr SF Monthly Rent
W 57th St & Avenue of the Americas $ 55
8,700
$ 39,875
W 54th St & Ninth Avenue $ 55
16,500
$ 75,625
Address $ / SF / Yr SF Monthly Rent
Seventh Ave & West 54th Street $ 49
4,100
$ 16,741
W 54th St & Eighth Avenue $ 49.5
4,200
$ 17,325
W 57th St & Avenue of the Americas $ 60
4,200
$ 21,000
Address $ / SF / Yr SF Monthly Rent
Seventh Ave & West 54th Street $ 46
2,000
$ 7,666
W 57th St & Seventh Avenue $ 60
2,200
$ 11,000
W 57th St & Avenue of the Americas $ 61
1,500
$ 7,625
Broadway & Between West 62nd Street $ 54
2,200
$ 9,900
Address $ / SF / Yr SF Monthly Rent
W 60th St & Broadway $ 45
13,800
$ 51,750
W 52nd St & Ninth Avenue $ 46
8,800
$ 33,733
Address $ / SF / Yr SF Monthly Rent
Broadway & West 53rd Street $ 39
5,800
$ 18,850
W 52nd St & Ninth Avenue $ 49
4,200
$ 17,150
Address $ / SF / Yr SF Monthly Rent
W 52nd St & Ninth Avenue $ 47.5
1,800
$ 7,125

Retail Spaces for Rent at 425 West 59th Street

Rent Retail 425 West 59th Street

Rent Medical Space at 425 West 59th Street

Nearby Office Tenants Leased
  • Dr. Dana Cohen leased 1,325 SF at 330 West 58th St
  • Fellowship for the Performing Arts leased 1,000 SF at 1674 Broadway
  • UBS leased 900,000 SF at 1285 Avenue of the Americas
  • Penguin Random House leased 603,605 SF at 1745 Broadway
  • Paul Weiss Rifkind Wharton & Garrison leased 550,000 SF at 1285 Sixth Ave
  • Morrison & Foerster LLP leased 435,038 SF at 250 West 55th St
  • Latham & Watkins leased 407,000 SF at 1271 Sixth Avenue
  • CBS Broadcasting Inc. leased 370,330 SF at 555 West 57th St
  • Willkie Farr & Gallagher leased 355,118 SF at 787 Seventh Ave
  • MMS USA Holdings leased 350,000 SF at 1675 Broadway
Nearby Retail Tenants Leased
  • Grom leased 800 SF at 240 Central Park South
  • Sabon leased 800 SF at 101 West 55th St
  • Blue Dog Cafe leased 700 SF at 152 West 57th St
  • Milos, Estiatorio leased 0 SF at 142 West 57th St
  • BNF Automotive Group leased 265,000 SF at 787 11th Avenue
  • Landmark Theatres leased 30,000 SF at 625 West 57th Street
  • Quick Park Broadway Garage LLC leased 29,902 SF at 1755 Broadway
  • Planet Fitness leased 29,400 SF at 423 West 55th St
  • T.J. Maxx leased 27,639 SF at 250 West 57th St
  • Maserati of Manhattan leased 25,000 SF at 619 West 54th St
$ / SF SF Monthly Rent
Please notify me when a new space is available
Tenant Broker’s Perspective: Return-to-office mandates are driving up rental prices at 425 West 59th Street. This trend is projected to continue. Opportunities for subleases remain available at 425 West 59th Street and in the nearby Columbus Circle neighborhood.
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Why Optimal Spaces Tenant Broker

  • Lease negotiation: full terms, renewals, expansion options
  • Cost analysis, inventory identification, negotiating scope
  • Risk mitigation against hidden pitfalls

Cost Savings

  • Negotiate 30+ leasing points to prevent hidden costs
  • Save 10–15% on total leasing costs
  • Save 100–200 hours filtering unviable spaces
  • Property access via broker databases and networks (off-market, subleases, future availability)

Alone or With Other Brokers

  • Managing agents owe fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
  • Inherent conflict of interest as most brokers represent landlords
  • Risk of weaker terms and overlooked hidden costs
  • Heavy workload falls on you while best spaces are missed

425 West 59th Street Property Overview

Building Address: 425 West 59th Street, New York NY 10019
Building Alternate Address: 425 W 59th St
Zip Code:10019
Neighborhood:Columbus Circle
Borough:Manhattan
Stories:10
Year Built:1984
Building Class:B

History of 425 West 59th Street, Manhattan, NYC

425 West 59th Street is part of the Mount Sinai West medical complex, originally established as Roosevelt Hospital in 1871. Founded through the will of James H. Roosevelt to provide care for sick and diseased persons in the community, Roosevelt Hospital opened its doors with 180 beds and quickly became a cornerstone of medical care in Midtown Manhattan.

The hospital complex occupies a full city block bordered by West 58th and West 59th Streets and 9th and 10th Avenues. The land was historically part of the old Somarindyck Farm, with roots tracing back to a 1667 land grant and subsequent ownership by the de Lancey family before being acquired for hospital development in the 19th century.

The site features notable historic medical buildings, such as the Syms Operating Theatre, built in 1892, which was renowned for its large surgical amphitheater designed for medical student observation. Over the years, the facility expanded and modernized, maintaining a legacy of medical education and patient care.

In 1979, Roosevelt Hospital merged with St. Luke's Hospital (founded 1846) and Women's Hospital (founded 1855) to form the St. Luke's-Roosevelt Hospital Center. This center later entered partnerships leading to its current identity as Mount Sinai West, named in 2015 following the merger with Mount Sinai Hospital.

Today, 425 West 59th Street houses outpatient services, including Radiology Associates West, continuing the site's long tradition of medical education and advanced patient care. Mount Sinai West is known for its teaching programs affiliated with the Icahn School of Medicine, offering residency and fellowship programs and pioneering treatments including robotics in radiation oncology since 2011.

425 West 59th Street, Manhattan, NYC

Located in Manhattan’s Midtown West area, 425 West 59th Street is a prominent address offering a variety of specialty medical and surgical services within a patient-friendly outpatient setting.

Medical Facilities and Services

Part of the Mount Sinai Health System, this location provides access to a wide range of specialized healthcare services, including:

  • CV Starr Hand and Upper Extremity Center
  • Digestive Diseases and Gastroenterology (Suite 3A)
  • Ear, Nose, and Throat / Otolaryngology (10th Floor)
  • Fetal Evaluation Unit with 3D and 4D fetal ultrasound (4th Floor)
  • Hematology/Oncology including Chemotherapy and Therapeutic Infusions (8th Floor)
  • Orthopedic Surgery focusing on various joints and sports medicine (5th Floor)
  • Pelvic Physical Therapy including biofeedback and manual therapy (Suite 3A)
  • Radiology services such as X-ray, MRI, 3D mammography, Ultrasound, Bone Densitometry, and Interventional Radiology (Suite 6C)
  • Rheumatology specializing in arthritis and osteoporosis (5th Floor)
  • Surgical specialties including colorectal, endocrine, oncologic, plastic, vascular, and urology surgery (7th Floor and Suite 4F)

Radiology Practice

The radiology practice at 425 West 59th Street, Suite 6C, offers comprehensive imaging services such as bone densitometry, full-service breast imaging, interventional radiology, musculoskeletal imaging, magnetic resonance imaging (MRI), ultrasound, and X-ray in a comfortable outpatient environment.

Location and Accessibility

Situated two blocks from Columbus Circle, this address is well-served by public transit, with nearby subway stations including 59 St-Columbus Circle, 7 Av, and 57 St-7 Av. Multiple bus lines also provide easy access to the area.

425 West 59th Street
New York, NY 10019
Manhattan, NYC

Building Amenities at 425 West 59th Street, Manhattan, NYC

Experience luxury living with sophisticated building amenities designed to enhance your lifestyle in Midtown Manhattan.

  • State-of-the-art fitness center equipped with cardio machines and free weights
  • Rooftop lounge featuring comfortable outdoor seating and stunning city views
  • Upscale residential spaces offering spacious and modern apartments

Additional features include convenient access to premier medical services at Mount Sinai Doctors located onsite, providing specialty outpatient care in a supportive environment.


425 West 59th Street, Manhattan, NYC is primarily known for its medical facilities rather than office tenants. The location is home to Mount Sinai Doctors West 59th Street, which offers a variety of medical services, including CV Starr Hand and Upper Extremity Center, Digestive Diseases - Gastroenterology, Ear, Nose, and Throat/Otolaryngology, Fetal Evaluation Unit, Hematology/Oncology, Orthopedic Surgery, Radiology, Rheumatology, Surgery, and Urology.

There are no prominent office tenants reported at this address, as it is predominantly used for medical services within the Mount Sinai Health System.


Internet Providers at 425 West 59th Street, Manhattan, NYC

The following internet service providers are commonly available in the area surrounding 425 West 59th Street, Midtown West, Manhattan, NY:

  • Verizon Fios: Offers high-speed fiber internet with plans starting around 300 Mbps, going up to 2 Gbps. Known for reliable service and good customer satisfaction.
  • Spectrum: Provides cable and fiber internet widely available in Manhattan, with speeds up to 1 Gbps and no data caps. Starting prices are around $30 to $50 per month.
  • Astound Broadband (formerly RCN): Offers both cable and fiber internet with speeds up to 1.5 Gbps. Known for competitive pricing and unlimited data usage.
  • AT&T U-verse: DSL and fiber options with speeds up to 1 Gbps, bundling options for internet, TV, and phone services, widely available in New York City.
  • T-Mobile Home Internet: Provides fixed wireless internet service, rated highly for customer satisfaction in the Upper West Side area near 425 West 59th Street.
  • Starry Internet: Fixed wireless provider with plans up to 1 Gbps, available in parts of Manhattan including Midtown West.

These providers offer a range of technologies including fiber, cable, DSL, and fixed wireless to meet diverse speed and service needs in Manhattan.


425 West 59th Street in Manhattan, NYC, is accessible by several transportation options:

Subway: The nearest subway station is 7 Av, which is just a 2-minute walk away. Other nearby subway stations include 59 St-Columbus Circle and 57 St-7 Av. Subway lines that stop near this location include the 1, A, B, W, C, and others.

Bus: Buses such as the M104, M20, and M57 stop nearby. For instance, the M11 bus stops at 10th Avenue and West 59th Street.

Path and Train: The PATH and West Hempstead Branch trains also pass nearby, though they might not be as frequently used for local commutes.

Cross Streets: The address is located between 10th Avenue and Columbus Circle, offering easy access to both the west and east sides of Manhattan.

Nearby Office Tenants Leased
  • Dr. Dana Cohen leased 1,325 SF at 330 West 58th St
  • Fellowship for the Performing Arts leased 1,000 SF at 1674 Broadway
  • UBS leased 900,000 SF at 1285 Avenue of the Americas
  • Penguin Random House leased 603,605 SF at 1745 Broadway
  • Paul Weiss Rifkind Wharton & Garrison leased 550,000 SF at 1285 Sixth Ave
  • Morrison & Foerster LLP leased 435,038 SF at 250 West 55th St
  • Latham & Watkins leased 407,000 SF at 1271 Sixth Avenue
  • CBS Broadcasting Inc. leased 370,330 SF at 555 West 57th St
  • Willkie Farr & Gallagher leased 355,118 SF at 787 Seventh Ave
  • MMS USA Holdings leased 350,000 SF at 1675 Broadway
Nearby Retail Tenants Leased
  • Grom leased 800 SF at 240 Central Park South
  • Sabon leased 800 SF at 101 West 55th St
  • Blue Dog Cafe leased 700 SF at 152 West 57th St
  • Milos, Estiatorio leased 0 SF at 142 West 57th St
  • BNF Automotive Group leased 265,000 SF at 787 11th Avenue
  • Landmark Theatres leased 30,000 SF at 625 West 57th Street
  • Quick Park Broadway Garage LLC leased 29,902 SF at 1755 Broadway
  • Planet Fitness leased 29,400 SF at 423 West 55th St
  • T.J. Maxx leased 27,639 SF at 250 West 57th St
  • Maserati of Manhattan leased 25,000 SF at 619 West 54th St

Double Agent Testimonial

Double Agent testimonial To Whom it May Concern: This is to give reference for Stephen Sunderland, who provided commercial real estate brokerage services to our firm, Double Agent. His work led to our signing of a five year lease and five year optional extension on 6,200 square feet of SOHO office space at a very competitive rate. I was extremely impressed by Stephen's professionalism and follow-through in helping us not only locate this space but also in bringing it to closing. He showed a good knowledge of our needs and through that avoided wasting our time showing us unsuitable properties. I would be glad to provide further reference for Stephen and you may feel free to call me about him. I can give him an unqualified recommendation. Best regards, Andrew Szabo Chairman and CEO Double Agent, Inc.

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