Rent Grand Central Medical
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Grand Central Medical Office Listings
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Medical Offices for Rent | ||||
| B | E 48th Street & Madison Avenue Floor 3 (full) | 8,000 | $ 43,200 | |
| B | E 45th Street & Second Avenue Floor 2 (full) | 6,800 | $ 22,000 | |
| B | Madison Ave & East 41st Street Floor 14 (full) | 5,700 | $ Negotiable | |
| A | Third Ave & East 41st Street Floor 16 | 5,500 | $ Negotiable | |
| Medium Medical Offices for Rent | ||||
| B | 4,000 | $ 18,200 | ||
| B | E 48th Street & Madison Avenue Floor 12 (full) | 3,800 | $ Negotiable | |
| B | Lexington Ave & East 41st Street Floor 23 (full) | 3,800 | $ 18,600 | |
| B | Madison Ave & East 40th Street Floor 11 | 3,000 | $ Negotiable | |
| C | E 46th Street & Fifth Avenue Floor 2 | 3,000 | $ Negotiable | |
| Small Medical Offices for Rent | ||||
| B | E 48th Street & Madison Avenue Floor 12 (full) | 2,800 | $ Negotiable | |
| B | E 46th Street & Fifth Avenue Floor 11 | 1,700 | $ Negotiable | |
| B | E 40th Street & Madison Avenue Floor 10 | 1,300 | $ 7,200 | |
| B | Park Ave & East 36th Street Floor 1 | 1,000 | $ 5,400 | |
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Medical Offices for Rent | ||||
| B | Lexington Ave & East 41st Street Floor 10 (full) | 6,100 | $ 21,800 | |
| B | Madison Ave & East 35th Street Floor 2 (full) | 5,700 | $ Negotiable | |
| Medium Medical Offices for Rent | ||||
| B | 3,500 | $ 16,800 | ||
| Small Medical Offices for Rent | ||||
| B | 1,500 | $ 7,200 | ||
| B | E 41st Street & Fifth Avenue Floor 11 | 1,400 | $ Negotiable | |
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Medical Offices for Rent | ||||
| B | E 23rd Street & Park Avenue Gramercy Park · Floor 10 (full) | 6,000 | $ 20,000 | |
| C | W 29th Street & Seventh Avenue Chelsea · Floor 12 | 6,000 | $ 15,000 | |
| B | E 23rd Street & Park Avenue Gramercy Park · Floor 10 (full) | 5,000 | $ 16,600 | |
| Medium Medical Offices for Rent | ||||
| B | W 57th Street & Avenue of the Americas Columbus Circle · Floor 3 | 4,100 | $ Negotiable | |
| B | W 36th Street & Eighth Avenue Penn Plaza/Garment · Floor 15 | 3,300 | $ 9,000 | |
| B | W 57th Street & Avenue of the Americas Columbus Circle · Floor 3 | 3,100 | $ 15,200 | |
| C | W 57th Street & Seventh Avenue Columbus Circle · Floor 4 | 3,000 | $ Negotiable | |
| Small Medical Offices for Rent | ||||
| B | Park Ave & East 79th Street Upper East Side · Ground floor | 1,200 | $ Negotiable | |
| C | W 29th Street & Seventh Avenue Chelsea · Floor 12 | 1,200 | $ Negotiable | |
| B | W 46th Street & Fifth Avenue Times Square · Floor 8 | 1,200 | $ 5,400 | |
| B | W 48th Street & Avenue of the Americas Plaza District · Floor 11 | 1,100 | $ 5,800 | |
| B | Park Ave & East 79th Street Upper East Side · Ground floor | 1,000 | $ Negotiable | |
Medical Tenants Rented / Leased Grand Central
- Moadel Eye Specialists leased 7,500 SF at 104-110 E 40th St
- Vein Treatment Clinic leased 5,950 SF at 290 Madison Ave
- California Cryobank leased 5,150 SF at 369 Lexington Ave
- Dr. Blau Plastic Surgery leased 4,826 SF at 535 Fifth Ave
- NYC Prosthodontics leased 3,500 SF at 275 Madison Ave
- Norman Marcus Pain Institute leased 3,000 SF at 30 E 40th St
- Richard M. Bronstein, DDS leased 2,884 SF at 551 Fifth Ave
- New York Blood Center leased 2,500 SF at 122 E 42nd St
- Your Dental leased 1,200 SF at 501 Fifth Ave
- Bryant Park Endonotics leased 900 SF at 30 E 40th St
- Integrative Physical Therapy of NYC leased 750 SF at 370 Lexington Ave
- Neurometric Evaluation Svc NY leased 450 SF at 30 E 40th St
Excellent opportunities for medical space still exist if you know where to look. Optimal Spaces has a proven track record of securing these spaces for our clients on the best possible terms.
We are dedicated tenant brokers, meaning we exclusively represent your interests, never the landlord’s.
Why choose Optimal Spaces?
- Significant Savings: We typically save clients 10–15% compared with what they could negotiate on their own.
- Time Efficiency: We eliminate 100–200 hours of blind, unnecessary research for you.
- No Conflict of Interest: We represent only you, not the landlord.
Optimal Spaces consistently delivers exceptional spaces and advantageous deals for our clients. See their success: New York Medical Office Testimonials .
Why Optimal Spaces Tenant Broker
- Lease negotiation: full terms, renewals, expansion options
- Cost analysis, inventory identification, negotiating scope
- Risk mitigation against hidden pitfalls
Cost Savings
- Negotiate 30+ leasing points to prevent hidden costs
- Save 10–15% on total leasing costs
- Save 100–200 hours filtering unviable spaces
- Property access via broker databases and networks (off-market, subleases, future availability)
Alone or With Other Brokers
- Managing agents owe a fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
- Inherent conflict of interest as most brokers represent landlords
- Risk of weaker terms and overlooked hidden costs
- Heavy workload falls on you while best spaces are missed