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Rent/Lease Office 345 Park Avenue South, New York, NY
Lease Office 345 Park Avenue South
Rent Sublease Office at 345 Park Avenue South
Nearby Sublease office Spaces for Rent
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Madison Ave & East 29th Street | $ 59 | 10,500 |
$ 51,625 |
| Park Ave S & Between East 19th Street | $ 60 | 7,700 |
$ 38,500 |
| Fifth Ave & East 21st Street | $ 69 | 7,300 |
$ 41,975 |
| Fifth Ave & East 19th Street | $ 77 | 8,800 |
$ 56,466 |
| Fifth Ave & East 16th Street | $ 42 | 10,100 |
$ 35,350 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Fifth Ave & East 21st Street | $ 71 | 5,200 |
$ 30,766 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| E 16th St & Park Avenue South | $ 64.5 | 3,400 |
$ 18,275 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Type of Space | Class A/month | Class B/month | Class C/month |
|---|---|---|---|
| Windowed office/person | |||
| Interior office/person | |||
| Team Rooms | |||
| Suites |
Nearby office Spaces for Rent
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Madison Ave & East 25th Street | $ 92 | 9,100 |
$ 69,766 |
| Park Ave S & East 20th Street | $ 81 | 13,000 |
$ 87,750 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Park Ave S & East 17th Street | $ 95 | 4,000 |
$ 31,666 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Madison Ave & East 29th Street | $ 61 | 8,300 |
$ 42,191 |
| E 23rd St & Park Avenue | $ 42 | 18,400 |
$ 64,400 |
| Broadway & East 20th Street | $ 70.5 | 18,200 |
$ 106,925 |
| Park Ave S & Between East 19th Street | $ 67 | 7,700 |
$ 42,991 |
| Park Ave S & East 27th Street | $ 75 | 8,700 |
$ 54,375 |
| Fifth Ave & East 29th Street | $ 79 | 12,500 |
$ 82,291 |
| Park Ave S & East 27th Street | $ 91 | 23,800 |
$ 180,483 |
| Park Ave S & East 27th Street | $ 69.5 | 13,100 |
$ 75,870 |
| E 26th St & Fifth Avenue | $ 125 | 12,100 |
$ 126,041 |
| Park Ave S & East 26th Street | $ 48.5 | 12,000 |
$ 48,500 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Broadway & Between East 19th Street | $ 76.5 | 5,300 |
$ 33,787 |
| E 23rd St & Park Avenue | $ 41 | 6,100 |
$ 20,841 |
| Broadway & East 20th Street | $ 75 | 3,700 |
$ 23,125 |
| Fifth Ave & East 29th Street | $ 72 | 4,700 |
$ 28,200 |
| Park Ave S & East 26th Street | $ 71 | 3,900 |
$ 23,075 |
| Park Ave S & East 26th Street | $ 75 | 2,700 |
$ 16,875 |
| University Pl & East 12th Street | $ 49 | 6,500 |
$ 26,541 |
| Broadway & East 18th Street | $ 71.5 | 2,500 |
$ 14,895 |
| Union Sq W & East 16th Street | $ 67 | 3,700 |
$ 20,658 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| Broadway & Between East 19th Street | $ 75 | 2,200 |
$ 13,750 |
| E 23rd St & Third Avenue | $ 45.5 | 2,400 |
$ 9,100 |
| Park Ave S & East 26th Street | $ 63 | 2,100 |
$ 11,025 |
| Fifth Ave & East 29th Street | $ 72.6 | 2,000 |
$ 12,100 |
| Broadway & East 18th Street | $ 73.5 | 1,800 |
$ 11,025 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| E 19th St & Broadway | $ 52.5 | 7,700 |
$ 33,687 |
| Madison Ave & East 30th Street | $ 39.5 | 11,000 |
$ 36,208 |
| E 23rd St & Lexington Avenue | $ 67.5 | 21,600 |
$ 121,500 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| E 23rd St & Park Avenue | $ 35 | 2,800 |
$ 8,166 |
| E 19th St & Broadway | $ 53.5 | 5,500 |
$ 24,520 |
| Fifth Ave & East 29th Street | $ 58 | 2,500 |
$ 12,083 |
| Fifth Ave & Between East 28th Street | $ 51.5 | 5,000 |
$ 21,458 |
| Address | $ / SF / Yr | SF | Monthly Rent |
|---|---|---|---|
| E 28th St & Park Avenue South | $ 38.5 | 2,300 |
$ 7,379 |
| Broadway & East 21st Street | $ 74.5 | 1,800 |
$ 11,175 |
Retail Spaces for Rent at 345 Park Avenue South
Rent Retail 345 Park Avenue South
Rent Medical Space at 345 Park Avenue South
- Digitas leased 240,000 SF
- Doral Bank leased 7,675 SF
- Elizabeth Arden leased 35,698 SF at 200 Park Avenue South
- Left/Right leased 34,000 SF at 39 West 19th Street
- The Atlantic leased 33,609 SF at 60 Madison Ave
- Enigma Technologies, Inc. leased 33,406 SF at 245 Fifth Ave
- Work Better leased 33,103 SF at 33 West 19th St
- The Yard leased 33,000 SF at 246 Fifth Avenue
- Looker Data Sciences, Inc. leased 33,000 SF at 40 West 25th St
- LinkShare Corporation leased 33,000 SF at 215 Park Ave S
- Petco leased 29,989 SF at 860 Broadway
- Progressive Plan Administrators Inc. leased 29,291 SF at 470 Park Ave S
- Free People leased 6,000 SF at 79 Fifth Ave
- Duane Reade leased 6,000 SF at 184 Fifth Ave
- Theory leased 5,500 SF at 139 Fifth Ave
- Silk Trading leased 5,400 SF at 936 Broadway
- Philippe Massoud restaurant leased 5,000 SF at 236 Fifth Ave
- Kellogg's NYC leased 5,000 SF at 31 East 17th Street
- Straussie's leased 4,954 SF at 41 Madison Avenue
- New York Community Bank leased 4,811 SF at 404 Park Ave South
- Schnipper's Quality Kitchen leased 4,790 SF at One Madison Ave
- Thursday Boots leased 4,300 SF at 48 West 21st Street
| $ / SF | SF | Monthly Rent |
|---|---|---|
| Please notify me when a new space is available | ||
Why Optimal Spaces Tenant Broker
- Lease negotiation: full terms, renewals, expansion options
- Cost analysis, inventory identification, negotiating scope
- Risk mitigation against hidden pitfalls
Cost Savings
- Negotiate 30+ leasing points to prevent hidden costs
- Save 10–15% on total leasing costs
- Save 100–200 hours filtering unviable spaces
- Property access via broker databases and networks (off-market, subleases, future availability)
Alone or With Other Brokers
- Managing agents owe a fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
- Inherent conflict of interest as most brokers represent landlords
- Risk of weaker terms and overlooked hidden costs
- Heavy workload falls on you while best spaces are missed
345 Park Avenue South, New York, NY Property Overview
| Building Address: | 345 Park Avenue South, New York NY 10010 |
| Building Name: | The Iselin Bldg |
| Building Alternate Address: | 345 Park Ave South, New York, NY |
| Zip Code: | 10010 |
| Neighborhood: | Gramercy Park |
| Borough: | Manhattan |
| Stories: | 12 |
| Year Built: | 1912 |
| Building Class: | A |
345 Park Avenue South, located in Midtown South, Manhattan, NYC, is a historic building originally completed in 1912 and designed by William H. Whittal. It was once known as the Armory Building.
The building underwent a full-scale renovation in 2021 by Deerfield, transforming it into a state-of-the-art office and life sciences hub known as CURE. This 12-story structure features lab-ready spaces, flexible office space, and a plethora of modern amenities. These include a rooftop terrace, lounge club, and fitness center, making it an attractive destination for life sciences, healthcare, and biotech companies.
Managed by RFR Realty and owned by Deerfield, 345 Park Avenue South offers approximately 300,000 square feet of office space. It is strategically located near the Flatiron District and Madison Square Park, with easy access to public transportation and upscale amenities.
345 Park Avenue South is located in the heart of Silicon Alley, Manhattan, providing a vibrant hub for innovation in the life sciences, digital health, and technology sectors.
This location is home to a premier life science facility, offering state-of-the-art lab spaces, ample amenities, and a collaborative community of leading companies. The building hosts a range of tenants involved in healthcare and biotech industries.
Originally built in 1912, the property was transformed into a Class A office and life sciences hub through a major renovation in 2021. It features 300,000 square feet of space across its 12 floors, including flexible office areas and ground-floor retail.
The area offers excellent connectivity, with easy access to major public transportation options and proximity to Madison Square Park.
Contact information for general inquiries about the building can be directed to its location at 345 Park Ave S, New York, NY 10010.
345 Park Avenue South in Manhattan offers a range of amenities:
- Rooftop terrace with flexible event space and stunning views of Manhattan.
- Lounge club and kitchen.
- Renovated lobby.
- Fitness center (available at an additional cost).
- Exclusive wine cellar.
- State-of-the-art conference center.
- Conference rooms and huddle spaces.
- NaCl Café on the 12th floor.
- 2nd floor Education Center.
345 Park Avenue South in Manhattan, NYC, is home to several notable tenants. The building, part of Deerfield's CURE. life sciences hub, hosts tenants such as:
- Deerfield
- ProTara Therapeutics
- Test Now and Go
- Bank of America Financial Center
- Helaina
Additionally, the Upland restaurant is located on the ground floor.
345 Park Avenue South, located in the heart of Manhattan, offers a prime spot for businesses and residents seeking reliable internet services. The area is covered by several top-tier internet providers, ensuring fast and consistent connectivity. Here are some of the internet providers likely available in the building:
Providers and Services:
- Verizon Fios: Known for its fiber-optic connections, offering speeds up to 2 Gbps and competitive pricing.
- Optimum: Offers high-speed plans up to 8 Gbps, ideal for demanding users.
- Astound Broadband Powered by RCN: Provides affordable high-speed plans with unlimited data and fiber-optic connections.
- Spectrum: Offers cable internet with speeds up to 1 Gbps and no data caps.
345 Park Avenue South, located in the heart of Midtown South, Manhattan, offers convenient access to multiple transportation options. The nearest subway stations include 28th Street, 23rd Street, and 33rd Street, with the 28th Street station being a 4-minute walk away. Bus stops are also nearby, including those on East 23rd Street and Madison Avenue, which is a 5-minute walk. The cross streets are Park Avenue South and Lexington Avenue, providing easy access to various amenities, restaurants, and parks in the area.
- Digitas leased 240,000 SF
- Doral Bank leased 7,675 SF
- Elizabeth Arden leased 35,698 SF at 200 Park Avenue South
- Left/Right leased 34,000 SF at 39 West 19th Street
- The Atlantic leased 33,609 SF at 60 Madison Ave
- Enigma Technologies, Inc. leased 33,406 SF at 245 Fifth Ave
- Work Better leased 33,103 SF at 33 West 19th St
- The Yard leased 33,000 SF at 246 Fifth Avenue
- Looker Data Sciences, Inc. leased 33,000 SF at 40 West 25th St
- LinkShare Corporation leased 33,000 SF at 215 Park Ave S
- Petco leased 29,989 SF at 860 Broadway
- Progressive Plan Administrators Inc. leased 29,291 SF at 470 Park Ave S
- Free People leased 6,000 SF at 79 Fifth Ave
- Duane Reade leased 6,000 SF at 184 Fifth Ave
- Theory leased 5,500 SF at 139 Fifth Ave
- Silk Trading leased 5,400 SF at 936 Broadway
- Philippe Massoud restaurant leased 5,000 SF at 236 Fifth Ave
- Kellogg's NYC leased 5,000 SF at 31 East 17th Street
- Straussie's leased 4,954 SF at 41 Madison Avenue
- New York Community Bank leased 4,811 SF at 404 Park Ave South
- Schnipper's Quality Kitchen leased 4,790 SF at One Madison Ave
- Thursday Boots leased 4,300 SF at 48 West 21st Street
Panelz USA Testimonial
To whom it may concern,
I want to thank Dorothy Kolev and Optimal Spaces Inc. for the excellent job they did in finding us our space. Dorothy made many presentations to us but never lost interest or gave up, she was fast and efficient in locating spaces that met our needs and corporate image, aggressive in negotiating on our behalf, and effective in communicating our needs to the landlord and getting our offer accepted. We are very satisfied with the services of Optimal Spaces Inc. I have recommended her and Optimal Spaces Inc. to friends and colleagues.
Sincerely,
David Yagerman
Panelz USA
SHOWROOM
20 West 22nd St, Suite 908
New York, NY 10010
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Optimal Spaces negotiates tenant deals, typically securing 10-15% savings. We find the perfect commercial space in New York, offering a wide range of options: office, educational, industrial, retail, medical, and loft spaces.