Midtown East Office Space for Rent
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Midtown East Office Space Listings
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Offices for Rent | ||||
| A | Fifth Ave & East 53rd Street Floor 4 (full) | 79,400 | $ Negotiable | |
| A | Park Ave & East 45th Street Floor 13 (full) | 71,900 | $ Negotiable | |
| C | Park Ave & East 51st Street Floor 4 (full) | 70,400 | $ Negotiable | |
| B | Third Ave & East 44th Street Floor 7 | 32,800 | $ Negotiable | |
| B | Third Ave & East 41st Street Floor 33 (full) | 19,700 | $ Negotiable | |
| A | Fifth Ave & West 55th Street Floor 17 | 13,200 | $ 108,200 | |
| A | Third Ave & East 50th Street Floor 40 (full) | 12,300 | $ 101,400 | |
| C | Park Ave & East 57th Street Floor 17 (full) | 11,100 | $ Negotiable | |
| B | Vanderbilt Ave & East 44th Street Floor 21 (full) | 10,300 | $ 69,400 | |
| C | Fifth Ave & East 39th Street Floor 7 (full) | 9,300 | $ 43,400 | |
| C | E 39th Street & Fifth Avenue Floor 8 (full) | 7,900 | $ 26,000 | |
| B | Madison Ave & East 46th Street Floor 10 (full) | 7,200 | $ 47,400 | |
| Medium Offices for Rent | ||||
| B | E 42nd Street & Lexington Avenue Floor 19 | 7,000 | $ Negotiable | |
| A | Third Ave & East 54th Street Floor 4 | 7,000 | $ Negotiable | |
| A | Third Ave & East 40th Street Floor 9 | 7,000 | $ Negotiable | |
| B | E 38th Street & Fifth Avenue Floor 2 (full) | 6,900 | $ Negotiable | |
| C | E 59th Street & Second Avenue Floor 3 (full) | 6,500 | $ 35,600 | |
| A | E 45th Street & Lexington Avenue Floor 44 | 5,700 | $ 44,800 | |
| C | Fifth Ave & East 42nd Street Floor 18 (full) | 5,700 | $ Negotiable | |
| A | Park Ave & East 56th Street Floor 2 | 4,200 | $ 34,200 | |
| C | E 59th Street & Madison Avenue Floor 17 | 4,000 | $ 20,400 | |
| B | 3,200 | $ 21,200 | ||
| B | E 42nd Street & Madison Avenue Floor 13 | 3,000 | $ 19,000 | |
| C | E 44th Street & Madison Avenue Floor 7 (full) | 2,700 | $ Negotiable | |
| Small Offices for Rent | ||||
| B | 2,500 | $ Negotiable | ||
| B | Fifth Ave & East 45th Street Floor 6 | 2,500 | $ Negotiable | |
| A | Madison Ave & East 57th Street Floor 25 | 2,400 | $ Negotiable | |
| A | Third Ave & East 49th Street Floor 12 | 2,400 | $ Negotiable | |
| C | 2,400 | $ Negotiable | ||
| A | E 44th Street & Lexington Avenue Floor 21 | 2,300 | $ 15,600 | |
| A | Park Ave & East 41st Street Floor 16 | 2,300 | $ 16,200 | |
| C | E 46th Street & Fifth Avenue Floor 5 | 2,200 | $ Negotiable | |
| B | Madison Ave & East 40th Street Floor 19 | 2,200 | $ 12,200 | |
| C | 2,200 | $ 9,000 | ||
| B | Fifth Ave & East 42nd Street Floor 14 | 1,800 | $ 10,200 | |
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Offices for Rent | ||||
| A | E 42nd Street & Second Avenue Floor 3 (full) | 78,900 | $ Negotiable | |
| A | E 42nd Street & Lexington Avenue Floor 12 (full) | 67,400 | $ Negotiable | |
| B | Madison Ave & East 39th Street Floor 7 (full) | 47,900 | $ Negotiable | |
| B | Third Ave & East 44th Street Floor 5 | 30,000 | $ Negotiable | |
| B | Fifth Ave & East 45th Street Floor 5 | 11,900 | $ 42,600 | |
| B | Fifth Ave & East 45th Street Floor 5 | 10,300 | $ 36,000 | |
| A | Park Ave & East 45th Street Floor 33 | 9,700 | $ 79,200 | |
| A | Madison Ave & East 59th Street Floor 15 | 8,300 | $ 68,400 | |
| C | E 59th Street & Madison Avenue Floor 17 | 8,200 | $ Negotiable | |
| Medium Offices for Rent | ||||
| A | Madison Ave & East 54th Street Floor 22 (full) | 7,000 | $ Negotiable | |
| B | E 57th Street & Lexington Avenue Floor 4 (full) | 7,000 | $ Negotiable | |
| A | Lexington Ave & East 41st Street Floor 11 | 6,900 | $ Negotiable | |
| A | Madison Ave & East 60th Street Floor 22 (full) | 6,800 | $ 50,400 | |
| B | E 44th Street & Third Avenue Floor 8 | 6,500 | $ Negotiable | |
| B | E 42nd Street & Lexington Avenue Floor 15 | 5,600 | $ 30,000 | |
| B | 4,200 | $ 22,600 | ||
| A | Park Ave & East 39th Street Floor 41 | 4,200 | $ 34,600 | |
| Small Offices for Rent | ||||
| A | E 53rd Street & Fifth Avenue Floor 30 | 2,500 | $ Negotiable | |
| A | E 49th Street & Fifth Avenue Floor 9 | 2,500 | $ Negotiable | |
| A | Madison Ave & East 49th Street Floor 39 | 2,200 | $ 14,000 | |
| B | 2,200 | $ Negotiable | ||
| B | Fifth Ave & East 45th Street Floor 7 | 2,100 | $ 9,000 | |
| B | 2,100 | $ 7,400 | ||
| A | Park Ave & East 40th Street Floor 23 | 2,000 | $ 11,200 | |
| B | Madison Ave & East 40th Street Floor 11 | 2,000 | $ Negotiable | |
| Class | Address | SF | Monthly Rent | |
|---|---|---|---|---|
| Large Offices for Rent | ||||
| A | Lexington Ave & East 47th Street Grand Central · Floor 2 (full) | 54,200 | $ Negotiable | |
| A | Park Ave & East 45th Street Grand Central · Floor 7 | 52,700 | $ Negotiable | |
| A | E 59th Street & Park Avenue Plaza District · Floor 21 (full) | 13,300 | $ 108,000 | |
| B | Fifth Ave & East 44th Street Grand Central · Floor 8 (full) | 13,100 | $ Negotiable | |
| B | E 42nd Street & Park Avenue Grand Central · Floor 8 | 12,200 | $ 69,000 | |
| B | E 60th Street & Fifth Avenue Plaza District · Floor 12 | 10,100 | $ Negotiable | |
| A | Fifth Ave & East 55th Street Plaza District · Floor 25 (full) | 8,700 | $ 70,600 | |
| B | Fifth Avenue & West 47th Street Plaza District · Floor 8 (full) | 8,000 | $ 42,000 | |
| Medium Offices for Rent | ||||
| A | Third Ave & East 47th Street Plaza District · Floor 23 (full) | 7,000 | $ Negotiable | |
| A | Third Ave & East 53rd Street Plaza District · Floor 24 | 7,000 | $ Negotiable | |
| B | E 41st Street & Fifth Avenue Grand Central · Floor 10 (full) | 6,800 | $ Negotiable | |
| A | Fifth Ave & West 52nd Street Plaza District · Floor 34 | 6,800 | $ 52,600 | |
| B | Fifth Ave & East 41st Street Grand Central · Floor 15 | 6,700 | $ Negotiable | |
| B | E 59th Street & Second Avenue Plaza District · Floor 6 | 3,200 | $ 24,800 | |
| B | Madison Ave & East 40th Street Grand Central · Floor 6 (full) | 3,000 | $ 18,200 | |
| A | Madison Ave & East 55th Street Plaza District · Floor 14 | 2,700 | $ 20,200 | |
| Small Offices for Rent | ||||
| B | Madison Ave & East 41st Street Grand Central · Floor 5 | 2,500 | $ Negotiable | |
| B | Lexington Ave & Lexington Avenue Plaza District · Floor 8 (full) | 2,500 | $ Negotiable | |
| A | E 56th Street & Park Avenue Plaza District · Floor 18 | 2,500 | $ Negotiable | |
| A | Lexington Ave & East 59th Street Plaza District · Floor 16 | 2,400 | $ Negotiable | |
| B | Park Ave & East 59th Street Plaza District · Floor 19 | 2,100 | $ 11,200 | |
| B | Madison Ave & East 49th Street Plaza District · Floor 10 | 2,000 | $ 10,800 | |
| A | Madison Ave & East 55th Street Plaza District · Floor 8 | 1,800 | $ 12,200 | |
| A | Fifth Ave & West 49th Street Plaza District · Floor 8 | 1,800 | $ 14,400 | |
Office Tenants Rented / Leased Midtown East
- Kreindler & Kreindler leased 14,078 SF at 485 Lexington Avenue
- Madison International Realty leased 25,000 SF at 300 Park Avenue
- Cambridge Associates leased 10,191 SF at 437 Madison Avenue
- CBRE leased 44,612 SF at 200 Park Avenue
- Raymond James leased 160,000 SF at 320 Park Avenue
- Tempus Labs leased 22,700 SF at 230 Park Avenue
- Lone Pine Capital leased 8,102 SF at 527 Madison Avenue
- AustralianSuper leased 7,400 SF at 527 Madison Avenue
- Axium Infrastructure leased 7,263 SF at 527 Madison Avenue
- Memorial Sloan Kettering leased 54,199 SF at 485 Lexington Avenue
- Addepar leased 40,000 SF at 335 Madison Avenue
- INTL FCStone leased 73,000 SF at 230 Park Avenue
- Great West Annuity leased 2,457 SF at 370 Lexington Avenue
- Cantor Fitzgerald leased 56,170 SF at 499 Park Avenue
Why Optimal Spaces Tenant Broker
- Lease negotiation: full terms, renewals, expansion options
- Cost analysis, inventory identification, negotiating scope
- Risk mitigation against hidden pitfalls
Cost Savings
- Negotiate 30+ leasing points to prevent hidden costs
- Save 10–15% on total leasing costs
- Save 100–200 hours filtering unviable spaces
- Property access via broker databases and networks (off-market, subleases, future availability)
Alone or With Other Brokers
- Managing agents owe a fiduciary duty to landlords, seeking maximum price and terms rather than tenant savings.
- Inherent conflict of interest as most brokers represent landlords
- Risk of weaker terms and overlooked hidden costs
- Heavy workload falls on you while best spaces are missed
About Midtown East
Geographic Boundaries
Midtown East is bounded by East 59th Street to the north, East 40th Street to the south (as per zoning distinctions), Fifth Avenue to the west, and the East River to the east. Broader definitions sometimes extend its southern boundary to 34th Street, taking in parts of Murray Hill, and maintain 59th Street as the northern edge near Central Park.
Businesses, Stores & Retailers
Midtown East hosts a high-density business corridor with flagship luxury retailers along Fifth Avenue, including Tiffany & Co. and Gucci. Specialty stores, niche shops and restaurants cluster in and around Grand Central Terminal. The area between Lexington and Third Avenues is dominated by corporate offices, finance firms, and boutique law practices.
Fine Dining
The neighborhood offers upscale dining at Smith & Wollensky (steakhouse), Aquavit (Scandinavian), and Sparks Steak House. Classic establishments like The Campbell Bar at Grand Central Terminal and The Grill in the Seagram Building emphasize historic ambiance, while newer rooftop venues near the UN Headquarters cater to diplomatic and business elites.
History of Major Attractions
Grand Central Terminal (1913) revolutionized rail travel with its Beaux-Arts design, while the Chrysler Building (1930) became an Art Deco icon. The United Nations Headquarters (1952) established Midtown East as a global diplomacy hub. St. Patrick's Cathedral (1879) on Fifth Avenue remains the neighborhood's best-known Gothic Revival landmark.
Architectural Typology
The area showcases early 20th-century skyscrapers like the Chrysler Building (1930) and post-war modernist towers such as the Seagram Building (1958). Recent additions include supertall residential condominiums like 432 Park Avenue (2015) and renovated office spaces adapting pre-war structures with contemporary tech infrastructure.
Notable Buildings
Beyond iconic landmarks, Midtown East contains the Waldorf Astoria Hotel (1931), the Lipstick Building (1986), and the Ford Foundation Building (1967). Tudor City’s residential complex (1920s-30s) pioneered high-rise urban living, while the Daily News Building (1930) exemplifies streamlined Art Deco newspaper architecture.
Transportation Infrastructure
Grand Central Terminal serves Metro-North Railroad and connects to subway lines 4/5/6/7/S. Bus routes M101/102/103 operate along Third Avenue, while the Roosevelt Island Tramway provides river crossings. Citibike stations and pedestrian plazas along 42nd Street facilitate intra-neighborhood mobility.
ZIP Code Distribution
Primary ZIP codes include 10017 (Grand Central area) and 10022 (east of Fifth Avenue). Adjacent codes cover 10065 (Upper East Side) and 10016 (Murray Hill), and several large office towers have their own building-specific ZIP codes. Corporate buildings often use specialized ZIP+4 codes for large tenants.
Corporate Presence
Midtown East is home to the headquarters of JPMorgan Chase and Estée Lauder. Major law firms and financial services giants such as MetLife occupy towers near Park Avenue. Many countries maintain their permanent missions to the United Nations in buildings near the UN complex, while tech firms increasingly lease space in renovated pre-war buildings.
Economic Profile
White-collar sectors dominate the neighborhood’s employment, and finance, legal services, and international trade account for a large share of office occupancy. Recent growth in coworking spaces and boutique hospitality caters to millennial professionals and diplomatic staff.
Office Buildings in Midtown East
- 200 Park Avenue
- 630 Fifth Avenue
- 30 Rockefeller Plaza
- 1290 Avenue of the Americas
- 767 Fifth Avenue
- 345 Park Avenue
- 277 Park Avenue
- 245 Park Avenue
- One Vanderbilt Avenue
- 399 Park Avenue
- 150 East 42nd Street
- 9 West 57th Street
- 335 Madison Avenue
- 660 Fifth Avenue
- 420 Lexington Avenue
- 919 Third Avenue
- 601 Lexington Avenue
- 230 Park Avenue
- 909 Third Avenue
- 299 Park Avenue
- 101 Park Avenue
- 280 Park Avenue
- 237 Park Avenue
- 375-391 Madison Ave
- 55 East 52nd Street
- 300 Madison Avenue
- 220 East 42nd Street
- 599 Lexington Avenue
- 725 Fifth Avenue
- 731 Lexington Avenue
- 520 Madison Avenue
- 590 Madison Avenue
- 405 Lexington Avenue
- 622 Third Avenue
- 90 Park Avenue
- 450 Lexington Avenue
- 343 Madison Ave
- 485 Lexington Avenue
- 437 Madison Avenue
- 235 East 42nd Street
- 51 West 52nd Street
- 100 Park Avenue
- 605 Third Avenue
- 375 Park Avenue
- 390 Madison Avenue
- 330 Madison Avenue
- 885 Second Avenue
- 550 Madison Avenue
- 750 Third Avenue
- 300 Park Avenue
- 666 Third Avenue
- 320 Park Avenue
- 1230 Avenue of the Americas
- 340 Madison Avenue
- 31 West 52nd Street
- 425 Park Avenue
- 575 Lexington Avenue
- 425 Lexington Avenue
- 40 West 57th Street
- 685 Third Avenue
- 979 Third Avenue
- 12 East 49th Street
- 140 East 45th Street
- 730 3rd Avenue
- 1 Rockefeller Plaza
- 757 Third Avenue
- 885 Third Avenue
- 875 Third Avenue
- 75 Rockefeller Plaza
- 65 East 55th Street
- 850 Third Avenue
- 110 East 59th Street
- 1350 Sixth Avenue
- 650 Madison Avenue
- 900 Third Avenue
- 350 Park Avenue
- 777 Third Avenue
- 825 Third Avenue
- 805 Third Avenue
- 535 Madison Avenue
- 150 East 58th Street
- 712 Fifth Avenue
- 745 Fifth Avenue
- 99 Park Avenue
- 285 Madison Avenue
- 660 Madison Avenue
- 800 Third Avenue
- 1270 Avenue of the Americas
- 250 Park Avenue
- 50 Rockefeller Plaza
- 575 Fifth Avenue
- 600 Third Avenue
- 780 Third Avenue
- 866 United Nations Plaza
- 717 Fifth Avenue
- 521 Fifth Avenue
- 1330 Avenue Of The Americas
- 600 Fifth Avenue
- 570 Lexington Avenue
- 555 Madison Avenue
- 60 East 42nd Street
- 633 Third Avenue
- 122 East 42nd Street
- 125 Park Avenue
- 711 Third Avenue
- 260 Madison Avenue
- 275 Madison Avenue
- 205 East 42nd Street
- 671-683 First Avenue
- 551 Fifth Avenue
- 295 Madison Avenue
- 1011 First Avenue
- 460 Park Avenue
- 304 East 45th Street
- 163-165 East 52nd Street
- 110 East 42nd Street
- 475 Fifth Avenue
- 505 Park Avenue
- 228 East 45th Street
- 130 East 59th Street
- 820 Second Avenue
- 270 Madison
- 211 East 43rd Street
- 235 East 45th Street
- 555 Fifth Avenue
- 801 Second Avenue
- 545 Fifth Avenue
- 489 Fifth Avenue
- 57 West 57th Street
- 425 East 61st Street
- 579 Fifth Avenue
- 52 Vanderbilt Avenue
- 216 East 45th Street
- 305 East 46th Street
- 14 East 60th Street
- 609 Fifth Avenue
- 501 Fifth Avenue
- 30 East 60th Street
- 830 Third Avenue
- 227 East 45th Street
- 815 Second Avenue
- 305-315 Madison Avenue
- 133 East 58th Street
- 155 East 55th Street
- 15 West 47th Street
- 11 East 44th Street
- 64 West 48th Street
- 286 Madison Avenue
- 441 Lexington Avenue
- 20 East 46th Street
- 369 Lexington Avenue
- 18 East 48th Street
- 6 East 39th Street
- 16 East 52nd Street
- 269-271 Madison Avenue
- 425 Madison Avenue
- 18 East 41st Street
- 590 Fifth Avenue
- 48 West 48th Street
- 12 East 41st Street
- 104-110 East 40th Street
- 309-315 East 48th Street
- 9 East 40th Street
- 16 East 40th Street
- 366 Madison Avenue
- 274 Madison Avenue
- 328-330 East 62nd Street
- 24-26 West 57th Street
- 30 Central Park S
- 120 East 56th Street
- 353 Lexington Avenue
- 71 West 47th Street
- 424 Madison Avenue
- 5 East 38th Street
- 49-55 West 47th Street
- 306 East 61st Street
- 20 West 55th Street
- 592 Fifth Avenue
- 22 West 48th Street
- 37 West 57th Street
- 6 East 45th Street
- 50 West 57th Street
- 110 East 55th Street
- 18-20 East 50th Street
- 315 East 46th Street
- 335 East 45th Street
- 724 Fifth Avenue
- 60 East 56th Street
- 42 West 48th Street
- 315 East 62nd Street
- 936-938 Third Avenue
- 30 East 40th Street
- 280 Madison Avenue
- 145 East 57th Street
- 25 West 52nd Street
- 1 East 42nd Street
- 6 West 48th Street
- 9 East 38th Street
- 20-24 East 60th Street
- 3-5 West 57th Street